Cystic fibrosis is associated with increased inflammatory responses to pathogen challenge. Here we revisited the role of IL-1b in lung pathology using the experimental F508del-CFTR murine model on C57BL/6 genetic background(Cftr or d/d), on double deficient for d/d and type 1 interleukin-1 receptor (d/d XIL-1R1), and antibody neutralization. At steady state, young adult d/d mice did not...

In order to help understand the phenomena of X-ray emission from early-type galaxies, we obtained an optically flux-limited sample of 34 elliptical and S0 galaxies, observed with high and low angular resolution detectors on the X-ray Röntgen Satellite (ROSAT). Our analysis of this sample, discussed previously, suggested that the most X-ray luminous galaxies were in rich environments. Here we in...

For nearly a century, lactobacilli (LB) in the oral cavity have been generally associated with dental caries. Here, we characterized the LB isolated from the saliva of 6 women with active caries using genetic-based taxonomical identification methods. From each subject, 30 isolates growing on Rogosa medium and presumed to be LB were analyzed. Of the 180 isolates, 176 were further characterized b...

This standard specifies the air interface of fixed (stationary) point-to-multipoint broadband wireless access systems providing multiple services. The medium access control layer is capable of supporting multiple physical layer specifications optimized for the frequency bands of application. The standard includes a particular physical layer specification applicable to systems operating between ...

At present, there are production processes to produce protein by Escherichia coli (E. coli) fermentation. Research on the design and optimization of the plasmid fermentation medium, however, is less advanced. The fermentation medium that is optimized for plasmid DNA production is different from the medium that is optimized for protein production. So, establishing a scientific and rational metho...

The effect of gold trichloride on DNA synthesis of human thymocytes and peripheral blood lymphocytes was tested. A stimulation was obtained in both cell types with a concentration of 6–50 μg/ml. Gold trichloride may thus not be used in a lymphocyte transformation test for the diagnosis of contact allergy. Correspondence to: Dr. Klas Nordlind, Department of Dermatology, Karolinska Sjukhuset, S–1...

The ability to efficiently generate integration-free induced pluripotent stem cells (iPSCs) from the most readily availablesource—peripheral blood—has the potential to expedite the advances of iPSC-based therapies. We have successfullygenerated integration-free iPSCs from cord blood (CB) CD34 cells with improved oriP/EBNA1-based episomal vectors (EV)using a strong spleen focus formi...

Several lactic acid bacteria produce exopolysaccharides (EPS), either attached to the cell wall or excreted into the environment as slime material. EPS produced by Lactobacillus delbrueckii subsp. bulgaricus (Lb. bulgaricus) and Streptococcus thermophilus play an important role in improving the texture and stability of yogurt and preventing syneresis (Cerning, 1990; Nakajima et al. 1990). The a...

Eshelby's formula gives the response of a single ellipsoidal elastic inclusion in an elastic whole space to a uniform strain imposed at in nity. Using a linear combination of results from two simple thought experiments, we show how this formula may be generalized to both poroelasticity and thermoelasticity. The resulting new formulas are important for applications to analysis of poroelastic and...

The present investigation was conducted to develop a protocol for rapid plant regeneration in potato. The newly emerge sprout of six potato cultivars were used as explant. Varietal response on in vitro regeneration under different hormonal concentration and combination were studied. MS medium supplemented with 0.5, 1.0, 1.5, 2.0, 4.0 mg L of KIN and IAA in combination of both were employed for ...