BACKGROUND/AIMS In this post-marketing observational study, the safety and effectiveness of memantine were evaluated in patients with Alzheimer's disease (AD). METHODS In a 6-month, observational, open-label study at 202 specialist sites in Greece, the effectiveness of memantine was evaluated using the Mini-Mental State Examination (MMSE) and the Instrumental Activities of Daily Living (IADL)...

Background People age differently, challenging the identification of those more at risk of rapid health deterioration. This study aimed to explore the heterogeneity in the health of older adults by using five clinical indicators to detect age-related variation and individual health trajectories over time. Methods Health of 3,363 people aged 60+ from the Swedish National study on Aging and Car...

This literature paper investigated the efficacy of 14 cognitive intervention programs administered to healthy elderly participants. PsycINFO and PubMed databases were searched using the following terms: cognitive training, cognitive stimulation, elderly, and aging. The majority of participants (13/14 studies) were recruited in community. Nine out of 14 studies targeted memory as the principal c...

Nearly 50% of older adults experience difficulty with sleeping, and 21% of older adults also experience cognitive complaints to which sleep difficulties can also contribute to poorer cognitive functioning. Combined, such sleep difficulties and age-related cognitive declines can contribute to poorer performance on everyday activities necessary for independence, quality of life, and successful ag...

OBJECTIVE This research explored the long-term benefits of engaging in proactive health promotion efforts among old-old residents of Sunbelt retirement communities to empirically test components of the Preventive and Corrective Proactivity (PCP) Model of Successful Aging. Specifically, we examined the contributions of exercise, tobacco use, moderate alcohol use, and annual medical checkups to m...

This cross-sectional study examined how three types of social support-social participation, emotional support, and caregiving support-were related to depressive symptoms in wives caring for their elderly husband and daughters caring for their elderly parent. We investigated whether different dimensions of social support affect mental health via different mechanisms and whether the context in wh...

BACKGROUND Recent research has begun to recognize the important influence of literacy levels and how they affect health and wellbeing, especially in older adults. Our study focuses on health and financial literacy, two domains of literacy which previous research has suggested may be significantly related to health and wellbeing. Our study examines the relation of health and financial literacy w...

People aged 90 and older represent a fast-growing population segment who deserve specific attention and research. Aging is associated with a progressive decrease in hemoglobin concentration, which predicts adverse outcome, such as mortality, morbidity, frailty and disability. Whether this association is independent from increased prevalence of comorbidity, causing both anemia and reduced physic...

OBJECTIVE to evaluate the associations of 18 activities of daily living with self-rated health in older people. DESIGN AND SETTING cross-sectional study of a representative sample of 781 people aged 65 or over (response rate: 89.9%). METHODS self-rated health was assessed by the question: "Overall, how would you rate your current health status-very good, good, fair, poor or very poor?" We u...

BMI is commonly used indicator of malnutrition and 18.5-24.9 kg/m(2) is generally regarded optimal. However, there is an ongoing debate on ideal range for elderly. BMI cut-off values vary also between ethnic groups. We aimed to investigate relationships between BMI, functional status and malnutrition in elderly living in a nursing home in Turkey. BMIs of 254 residents were calculated. Chronic d...