Full understanding of complex biological interactions frequently requires multi-color detection capability in doing single-molecule fluorescence resonance energy transfer (FRET) experiments. Existing single-molecule three-color FRET techniques, however, suffer from severe photobleaching of Alexa 488, or its alternative dyes, and have been limitedly used for kinetics studies. In this work, we de...

The first commercial excimer laser was introduced 40 years ago by Lambda Physik (now Coherent; Santa Clara, CA). Interestingly, its developers— Bernd Steyer and Dirk Basting—were both chemists whose main goal was to develop a light source for photochemistry and dye laser pumping. As soon as excimer lasers entered the market, Lambda Physik began to investigate other possible uses for a powerful ...

PURPOSE To perform a comparative clinical analysis of the safety, efficacy, and predictability of two surgical procedures (ie, small incision lenticule extraction [SMILE] and femtosecond laser-assisted LASIK [FS-LASIK]) to correct myopia. METHODS Sixty eyes of 31 patients with a mean spherical equivalent of -5.13 ± 1.75 diopters underwent myopia correction with the SMILE procedure. Fifty-one ...

Purpose. To investigate the visual quality after SMILE and Femto-LASIK. Methods. About 123 eyes from 63 patients were enrolled in this study. The parameters were measured preoperatively and 1 week, 1 month, and 3 months postoperatively using Sirius System. Results. The MTF curve increase slightly from low to high frequency at 3 mm and 6 mm pupil diameter after SMILE surgery (P < 0.05) during th...

The paper investigates the fabrication of Selective Laser Melting (SLM) titanium alloy Ti6Al4V micro-lattice structures for the production of lightweight components. Specifically, the pillar textile unit cell is used as base lattice structure and alternative lattice topologies including reinforcing vertical bars are also considered. Detailed characterizations of dimensional accuracy, surface ro...

PURPOSE To assess the reliability and reproducibility of static cyclotorsion correction (SCC) measurements made using the Schwind Amaris Excimer laser in patients undergoing LASIK or PRK, and compare the outcomes of treating astigmatism with and without SCC. METHODS Eighty eyes of 40 patients were included in this study. All eyes underwent 2 or 3 sets of five measurements: before and after sp...

PURPOSE To compare the biomechanical properties of the cornea after small-incision lenticule extraction (lenticule extraction group) with those after femtosecond laser-assisted laser in situ keratomileusis (femtosecond LASIK group). SETTING Tianjin Eye Hospital & Eye Institute, Tianjin Key Laboratory of Ophthalmology and Visual Science, Tianjin Medical University, Tianjin, China. DESIGN Pro...

We present 2 cases that came to our institute for refractive surgery and were discovered to have serious systemic conditions requiring immediate intervention. On examination, prolactinoma of the pituitary gland was seen in one patient and multiple sclerosis was diagnosed in the other patient. Prompt treatment of the conditions led to improvement in the neuro-ophthalmic disorders. We recommend a...

With the aging of the population worldwide, there is increased interest in surgical correction of presbyopia among our patients. To that end, in recent years several models of intrastromal corneal inlays have been introduced to the market with the purpose of providing those patients with clear crystalline lenses the opportunity to achieve better UNVA without diminishing distance vision. Each of...

PURPOSE The purpose of this study was to establish the alterations of oxidative stress-related markers in keratoconus (KC) corneas. METHODS A total of 6 healthy and 11 ectatic corneas (7 KC and 4 post-LASIK) were studied. Different oxidative stress-related markers were determined to assess their implication in the KC pathophysiology. Total antioxidant capacity and total nitrites present in th...