1. The effects of locally induced alterations in skin temperature on the postural changes in skin blood flow of the foot were assessed in 38 healthy subjects in a constant-temperature environment (22 +/- 0.5 degrees C, mean +/- SD). 2. Moderate local cooling and warming of the foot (26-36 degrees C) was induced by blowing cold or hot air. Higher ranges of temperature (38-44 degrees C) were achi...

The influence of garment pressure on human physiological activities has attracted researchers from many areas. In this study, to investigate the effect of external pressure on skin blood flow (SBF) at lower limb in different postures, external pressure was exerted on lower limb in supine and sitting postures using sphygmomanometer. Five undergraduate male students volunteered to participate in ...

Reactive hyperaemia, which occurs after a period of arterial occlusion is the result of an autoregulatory mechanism, involving local factors and autonomic nerve system control. To determine this autoregulatory mechanism in cutaneous blood flow in premature newborns measured the cutaneous reactive hyperaemia response after a 1 min occlusion, using a diode laser Doppler flowmeter applied to the s...

Pressure ulcers continue to be a major health care problem. This paper describes an animal model and surface pressure delivery system for the production of experimentally derived pressure ulcers. A method for inducing dermal pressure lesions on the fuzzy rat was developed using a computer-controlled displacement column which produced a constant tissue interface pressure. The pressure column con...

Functional studies have yet to be undertaken to establish which brain region subserves the parasympathetic regulation of the cerebral circulation. Using 31 anesthetized rats with precluded cervical sympathetic trunks, we therefore attempted to perform chemical stimulation of the greater petrosal nerve (GPN) cell group, which is a subgroup of the superior salivatory nucleus and sends off axons l...

INTRODUCTION Insufficient mesenteric perfusion is a dramatic complication in critically ill patients. Hydrogen sulfide, a newly recognized endogenous gaseous mediator, acts as an intestinal vasoactive agent and seems to protect against mesenteric ischemic damage. We investigated whether sodium hydrogen sulfide, a hydrogen sulfide donor, can improve mesenteric perfusion in an experimental model ...

This investigation examined the effects of loud sound of different frequencies and intensities on cochlear blood flow as measured by the laser Doppler flowmeter. Cochlear blood flow was measured in anesthetized guinea pigs during a 1 h exposure to either a 2, 4, or 12 kHz pure tone or high-pass noise (10-40 kHz) at 90, 103, or 110 dB SPL. Cochlear function was assessed using the compound action...

periodontal inflammation is associated with morphological changes in the blood vessels which may influence the regulation of gingival blood flow (gbf). our aim was to adapt the heat provocation test to the human gingiva to assess vascular reactivity in periodontal inflammation. method: gbf was recorded by laser doppler flowmetry before and after heat provocation in healthy volunteers (n = 50). ...

Microcirculatory disturbances are important early pathophysiological events in various organs during acute pancreatitis (AP). The aim of the study was to investigate an influence of L-arginine (nitric oxide substrate) and N(G)-nitro-L-arginine (L-NNA, nitric oxide synthase inhibitor) on organ microcirculation in experimental acute pancreatitis induced by four consecutive intraperitoneal cerulei...

Transient local anoxia of the cochlea was induced by pressing the labyrinthine artery, and compound action potential (CAP) or endocochlear potential (EP) was measured before and after transient local anoxia ranging from 5 to 60 min using 106 albino guinea pigs. The complete interruption of the cochlear blood flow by this procedure and its full restoration after releasing the pressure on the art...