We consider the problem of designing an allocation rule or an “online learning algorithm” for a class of bandit problems in which the set of control actions available at each time t is a convex, compact subset of R. Upon choosing an action x at time t, the algorithm obtains a noisy value of the unknown and time-varying function ft evaluated at x. The “regret” of an algorithm is the gap between ...

OBJECTIVE Family caregivers often accompany patients to medical visits; however, it is unclear whether caregivers rate the quality of patients' care similarly to patients. This study aimed to (1) quantify the level of agreement between patients' and caregivers' reports on the quality of patients' care and (2) determine how the level of agreement varies by caregiver and patient characteristics. ...

The study aims to investigate the underlying mechanism involved in the early secretory antigenic target-6 (ESAT-6) in renal injury through regulation of the expression of miR-155 through the oll-like receptor (TLR)-4 (TLR4)/myeloid differentiation factor 88 (MyD88) signaling pathway in Mycobacterium tuberculosis (MTB)-infected mice. Sixty C57BL/6 mice with MTB-induced renal injury were randomly...

PURPOSE The purpose of this study was to determine whether histone deacetylase (HDAC) inhibitors (HDACI) such as vorinostat or entinostat (SNDX-275) could increase the lethality of the dual Bcr/Abl-Aurora kinase inhibitor KW-2449 in various Bcr/Abl(+) human leukemia cells, including those resistant to imatinib mesylate (IM). EXPERIMENTAL DESIGN Bcr/Abl(+) chronic myelogenous leukemia (CML) an...

Untapped pine needles with high potential for energy generation in the hilly area are not only a waste of resource but also increase the chance of environmental hazards as forest fires and GHG emission. This study is conducted to propose a new hybrid system (PV/Wind/Biomass) using abundant pine needle resource as a replacement of existing roof-mounted PV/wind hybrid system and analyse the feasi...

12 Background 13 Lithium di-silicate dental ceramics bonding, realized by using different resins, is strictly dependent 14 on micro-mechanical retention and chemical adhesion. The aim of this in vitro study was to 15 investigate the capability of a 1070 nm fiber laser for their surface treatment. 16 Methods 17 Samples were irradiated by a pulsed fiber laser at 1070 nm with different parameters ...

Let L/K be a field extension. A K-vector space W can be extended to an L-vector space L⊗KW , and W embeds into L⊗KW by w 7→ 1⊗w. Under this embedding, when W 6= 0 a K-basis {ei} of W turns into an L-basis {1⊗ ei} of L⊗KW . Passing from W to L⊗KW is called ascent. In the other direction, if we are given an L-vector space V 6= 0, we may ask how to describe the K-subspaces W ⊂ V such that a K-basi...

We consider the Kiefer-Wolfowitz (KW) stochastic approximation algorithm and derive general upper bounds on its meansquared error. The bounds are established using an elementary induction argument and phrased directly in the terms of tuning sequences of the algorithm. From this we deduce the nonnecessity of one of the main assumptions imposed on the tuning sequences by Kiefer and Wolfowitz [Kie...

Diet quality indices can predict nutritional adequacy of usual intake, but validity should be determined. The aim was to assess the validity of total and sub-scale score within the Australian Recommended Food Score (ARFS), in relation to fasting plasma carotenoid concentrations. Diet quality and fasting plasma carotenoid concentrations were assessed in 99 overweight and obese adults (49.5% fema...