The MEDLINE database was searched using the key words: 'obesity' and 'knee arthroplasty'. 41 articles focused on the topic were reviewed; most studies were prospective case series (providing low-level evidence) and 3 were systematic reviews. 16 studies reported no adverse association between obesity and total knee arthroplasty (TKA) outcome, whereas 24 studies reported a poorer TKA outcome in o...

OBJECTIVE To evaluate the clinical effects of intraarticular platelet-rich plasma (PRP) injections in a small group of patients with primary and secondary osteoarthritis. Most of the current treatments for osteoarthritis are palliative and attack the symptoms rather than influencing the biochemical environment of the joint. Autologous platelet-rich plasma has emerged as a treatment option for t...

BACKGROUND Prosthetic design for the use in primary total knee arthroplasty has evolved into designs that preserve the posterior cruciate ligament (PCL) and those in which the ligament is routinely sacrificed (posterior stabilized). In patients with a functional PCL the decision which design is chosen depends largely on the favour and training of the surgeon.The objective of this study is to de...

BACKGROUND Patients with knee osteoarthritis (OA) report knee pain, limitation in physical activities and low quality of life. The two primary treatments for knee OA are non-surgical treatment (e.g., exercise) and surgery (total knee arthroplasty (TKA)); however, national guidelines recommend non-surgical treatment to be tried prior to surgical procedures. Patients with knee OA are characterize...

BACKGROUND Joint awareness was recently introduced as a new concept for outcome assessment after total knee arthroplasty (TKA). Findings from qualitative and psychometric studies suggest that joint awareness is a distinct concept especially relevant to patients with good surgical outcome and patients at late follow-up time points. The aim of this study was to improve the understanding of the co...

BACKGROUND Osteoarthritis (OA) of the knee is the most prevalent joint disorder. Previous studies suggest that bromelain, a pineapple extract, may be a safer alternative/adjunctive treatment for knee OA than current conventional treatment. AIM To assess the efficacy of bromelain in treating OA of the knee. DESIGN Randomized, double-blind placebo-controlled trial. METHODS Subjects (n = 47)...

We previously compared the component alignment in total knee replacement using a computer-navigated technique with a conventional jig-based method. We randomly allocated 71 patients to undergo either computer-navigated or conventional replacement. An improved alignment was seen in the computer-navigated group. The patients were then followed up post-operatively for two years, using the Knee Soc...

BACKGROUND Matrix-assisted autologous chondrocyte transplantation (MACT) is a surgical treatment option for articular cartilage lesions of the knee joint. PURPOSE To investigate mid- to long-term clinical outcomes of MACT in the patellofemoral (PF) and tibiofemoral (TF) joints. STUDY DESIGN Systematic review; Level of evidence, 4. METHODS A systematic review was performed by searching Pub...

Background: The role of wound drainage after total knee arthroplasty is still considered controversial as althoughclosed drainage systems have been believed to be effective in decreasing the post-operative complications, they couldalso facilitate the bleeding and increase the rate of transfusion and infection. We have conducted the current study tocompare the outcomes superficial subcutaneous, ...