In this study, we investigated the effectiveness of gabapentin (Neurontin), administered spinally with a microdialysis fiber, in reducing nociceptive behavioral responses induced by a knee joint inflammation model. This model is produced by injection of the knee joint with kaolin and carrageenan in rats. The resultant knee joint inflammation produces a secondary hyperalgesia to radiant heat app...

Background. Osteoarthritis (OA) is a disease which influences the performance of the knee joint. Moreover, the force and moments applied on the joint increase in contrast to normal subjects. Various types of knee orthoses have been designed to solve the mentioned problems. However, there are other problems in terms of distal migration during walking and the alignment of the orthosis which canno...

The Adaptive knee joint is a microprocessor-controlled prosthetic knee that incorporates both pneumatic and hydraulic control in one electronic unit. Pneumatic control is said to provide control during swing phase and the hydraulic control during the stance phase of the gait. This hybrid controller is triggered by a computer contained within the knee that responds to input from force, time and ...

INTRODUCTION Marked weakness of the quadriceps muscles is typically observed following injury, surgery or pathology affecting the knee joint. This is partly due to ongoing neural inhibition that prevents the central nervous system from fully activating the quadriceps, a process known as arthrogenic muscle inhibition (AMI). This study aimed to further investigate the mechanisms underlying AMI by...

Purpose: Proprioception is a part of the somatosensory system responsible for sending information to the central nervous system to monitor the status of various body parts relative to each another. One of the main causes of impaired proprioception is fatigue. In the following study, the effects of fatigue on quadriceps muscle and hence on knee proprioception in healthy subjects was studied.&nbs...

background: chondromalacia patella is the most common cause of mechanical knee pain in young women. q angle and knee alignment are important clinical parameters for biomechanics of the patellofemoral joint. objective: to identify the prevalence of knee malalignment and to find out if there is a correlation between knee mal alignment and q angle with age at onset of disease. methods: all patient...

Osteoarthritis (OA) a common disease of aged population and one of the leading causes of disability. Incidence of knee OA is rising by increasing average age of general population. Age, weight, trauma to joint due to repetiting movements in particular squatting and kneeling are common risk factors of knee OA. Several factors including cytokines, leptin, and mechanical forces are pathogenic fact...

Background: A 36-year-old woman presented to the orthopedic department with painful impairment of the left knee. The pain to the medial side of the knee and locking of the knee joint had started after a distortion of the knee during a game of soccer 2 weeks earlier. On clinical exami nation, the left knee showed a flexion/extension range of 110/0°. On palpation and rotation of the knee joint, t...