The present research was aimed at the enhancement of the dissolution rate of atorvastatin calcium by the solid dispersion technique using modified locust bean gum. Solid dispersions (SD) using modified locust bean gum were prepared by the modified solvent evaporation method. Other mixtures were also prepared by physical mixing, co-grinding, and the kneading method. The locust bean gum was subje...

The effect of screw configuration on granule size distribution (GSD) using gPROMS FormulatedProduct (gFP) software to perform optimization, estimation complex processes, and analyses is evaluated. Twin-screw granulation modeling was used investigate the contribution liquid-to-solid (L/S) ratio GSD. Lactose Avicel were granulating materials. Twelve different configurations investigated under thr...

Owing to the increasing demand for wholewheat flours (WWF) in bread-making, techniques are needed improve WWF's poor technological properties and resulting bread quality. We tested effect of a common bakers' strategy WWF performance: adding part water recipe during kneading operation. First, operating conditions were optimized perform gradual addition. The dough sample was second trial make an ...

Labor pain is a complex phenomenon with sensory, emotional and perceptive components considered one of the most serious types pain. Severe can affect increase in heart rate, respiratory system, blood pressure cause stress inhibit release hormone oxytocin which results inadequate contractions disruption cervical dilatation. The aim study was to assess effectiveness kneading technique deep breath...