Background: Microparticles are small (0.1–1 μm), extracellular vesicles that are used as diagnostic and prognostics markers of kidney diseases and kidney transplantation. They contain cytoplasm and surface markers of their cells of origin. The aim of this review is to describe the functional capabilities of microparticles in kidney diseases with focus on kidney transplantion. Main body: Micropa...

Cystic kidney diseases affect patients of all age groups with the onset spanning from prenatal disease to late adulthood. Autosomal-dominant polycystic kidney disease (ADPKD) is by far the most common renal cystic disease. However, there are various cystic kidney diseases, the onset of which occurs at different times in life and depends on the type of the disease and the causative genes involve...

The ability to define the pathological basis of kidney diseases has advanced substantially since the completion of the Human Genome Project. Moreover, advances in technology have been greater in the past decade than has ever been seen in modern medicine. These advances combine to open the door to a richer understanding of both normal and pathological processes involved in kidney function and co...

1Department of Nephrology, Transplantation Medicine and Immunology, G. R. Doshi and K. M. Mehta Institute of Kidney Diseases & Research Centre [IKDRC],Ahmedabad, Gujarat, India 2Department of Pathology, Laboratory Medicine, Transfusion Services, Immunohematology, G. R. Doshi and K. M. Mehta Institute of Kidney Diseases & Research Centre [IKDRC],Ahmedabad, Gujarat, India 3Senior Research Officer...

From the Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD. Address reprint requests to Dr. Liang at the Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bldg. 10-9B16, 10 Center Dr., Bethesda, MD 20892-1800, or at [email protected].

From the Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD. Address reprint requests to Dr. Liang at the Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bldg. 10-9B16, 10 Center Dr., Bethesda, MD 20892-1800, or at [email protected].

Objective: The incidence and prevalence of kidney stone is increasing worldwide. After the first recurrence the risk of subsequent relapses is higher and the time period between relapses is shortened. Urinary stones can be severely painful and make a huge economic burden. The stone disease may increase the vulnerability of patients to other diseases such as renal failure. Medicinal herbs are ri...