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تعداد نتایج: 3864572 فیلتر نتایج به سال:
Abstract: Aim/Background: Metastasis is the main reason of death in cancer with a key challenge to target it precisely by available treatments. The current study was designed assess anti-metastatic potentials synthesized chalcones, Ch-1 and Ch-2. Materials Methods: In vitro included cytotoxicity, scratch wound assay cell cycle analysis vivo performed C57BL/6 mice B16-F10 induced metastatic lung...
In this study we investigated histopathological changes of mice ovarian tissues following long-term administration of copper sulfate and induction of chronic copper poisoning. The study comprised of three different groups of twenty one mice as follows: The first group (Group 100) which treated by gavage with copper sulfate at a dose of 100 mg kg-1 for 5 weeks. The second group (Group 200), whic...
Sorbitol content was determined in porcine urinary bladder epithelial cells immediately after death of the animals and after primary culture of the cells at different osmolalities. In both instances, sorbitol content increased with urine and medium osmolality, respectively. For example, at 300 mosmol/kg the cultured cells contained 0.84 +/- 0.02 nmol/mg protein, at 600 mosmol/kg contained 21.7 ...
The purpose of this study was to determine the effect of two different intensities of physical activity on circulating endothelial progenitor cells (EPC) in healthy young women. For this purpose, 15 female students from volunteers were randomly selected via questionnaire (group 1: mean age 22 ±1/8 years, BMI 20/81±1/91 kg/m2, n = 8. group 2: mean age 21 ±1/5 years, BMI 20/38 ± 1/66 kg/m2, ...
IL-18 production may enhance immune system defense against KG-1 cells ; NB4 cells, which are associated with good prognosis, do not produce IL-18. In this study, we treated KG-1 cells with IL-18 and used microarray technology to assess subsequent effects on gene expression. In UniGene-array of 7488 human genes, expression of 57 genes, including stress related genes, increased at least 2-fold, w...
Gh.R. Asadikaram [1] , M. Asiabanha [2] , A. Rahnema [3] , Z. Shaebani Shahrbabaki [4] , M. Mahmoodi [5] , H.A. Sasan [6] Received: 12/06/2010 Sent for Revision: 27/11/2010 Received Revised Manuscript: 26/01/2011 Accepted: 03/02/2011 Background and Objectives : Apoptosis is a physiological mechanism of cell death and it can be triggered by a variety of internal and external stimuli. I...
Backgrounds and Aim: One of the effective strategies for targeting chemotherapy in the treatment of cancer is the use of lipid nano-carriers. In this study, an optimal formulation of niosomal drug containing doxorubicin has been developed to better fight cancer cells. Material and Methods: Niosomal vesicles were prepared using phosphatidylcholine (22%), span60 (52/5%), cholesterol (22/5%) and ...
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