abstract infiltration process is one of the most important components of the hydrological cycle. on the other hand, the direct measurement of infiltration process is laborious, time consuming and expensive. in this study, the possibility of predicting cumulative infiltration in specific time intervals, using readily available soil data and artificial neural networks (anns) was investigated. for...

The effect of ketamine (1-100 µM), which has NMDA receptor antagonist properties, on synaptic transmission and long-term potentiation (LTP) in CAl area of rat hippocampus was examined in vitro. Field potentials were recorded in pyramidal cell layer following Schaffer collateral stimulation. Primed-burst stimulation (PEs) was used for induction of LTP. The amplitude of population spiks (PS) was ...

BACKGROUND Recent substance abuse research indicates gender differences in the substance-related epidemiology, biological responses, progression to dependence, medical consequences and treatments. Studies exploring human sex-different responses to ketamine are rare and there has been no systemic survey of gender differences in ketamine use. Determining whether females are more susceptible than ...

TOTHEEDITOR: Newport et al. (1), in their systematic review of N-methyl-D-aspartate antagonists used for the treatment of depression that was published in the October 2015 issue of the Journal, noted that ketamine does indeed have a rapid but transient antidepressant effect. However, the authors cautioned against using ketamine as a novel antidepressant for treatment-resistant depression becaus...

abstract infiltration is one of the most important phenomena which is affected by the soil physical and hydraulic characteristics. measurement of infiltration needs the high cost and is time consuming, therefore estimation of infiltration is necessary. also, due to variability of soil moisture, it is important to determine the appropriate model for the estimating the infiltration rate. the pres...

OBJECTIVE To evaluate the literature regarding the efficacy and safety of intravenous ketamine for treatment-resistant major depressive disorder (MDD). DATA SOURCES A MEDLINE search (1966-September 2011) was performed using the terms treatment-resistant depression and ketamine. The search was restricted to articles published in English and reporting on use of ketamine in humans. STUDY SELEC...

OBJECTIVES Ketamine and other NMDA (N-methyl-D-aspartate) antagonists produce fast-acting antidepressant-like effects, although the underlying mechanism is unclear. Furthermore, high affinity NMDA antagonists such as ketamine are associated with psychotomimetic effects. To date the link between the antidepressant and psychotomimetic effects of ketamine has not been explored. We examined the rel...

Intravenous ketamine infusions have been used extensively to treat often-intractable neuropathic pain conditions. Because there are many widely divergent ketamine infusion protocols described in the literature, the variation in these protocols presents a challenge for direct comparison of one protocol with another and in discerning an optimal protocol. Careful examination of the published liter...

BACKGROUND Previous studies have demonstrated inconsistent neurophysiologic effects of ketamine, although discrepant findings might relate to differences in doses studied, brain regions analyzed, coadministration of other anesthetic medications, and resolution of the electroencephalograph. The objective of this study was to characterize the dose-dependent effects of ketamine on cortical oscilla...

Ketamine is an ionotropic glutamatergic N‑methyl‑D‑aspartate receptor antagonist, which is widely used among recreational drug abusers. Ketamine abusers exhibit substantially reduced bladder capacity, which can lead to urinary frequency. The molecular pathogenesis of ketamine‑induced cystitis has been scarcely reported. Given previous clinical findings, it may be hypothesized that pathological ...