Kennedy disease (KD, or spinal and bulbar muscular atrophy) is caused by a CAG/polyglutamine expansion in the androgen receptor (AR) gene. Both motoneurons and muscles are affected by KD, but where mutant ARs act to initiate this disease is not clear. We discuss recent insights into this disease with two main themes. (1) KD is androgen-dependent, suggesting that blocking androgen action may be ...

Kennedy and Pynte [Kennedy, A., & Pynte, J. (2008). The consequences of violations to reading order: An eye movement analysis. Vision Research, 48, 2309-2320] presented data that they suggested pose problems for models of eye movement control in reading in which words are encoded serially. They focus on situations in which pairs of words are fixated out of order (i.e., the first word is skipped...

ii ACKNOWLEDGEMENTS I would like to express my appreciation to my major professor Dr. R. Wes Harrison. I want to thank him for trusting my professional skills, for his guidance, advice, and time throughout this research. I must also extend my gratitude to my committee members, Dr. Roger Hinson, and Dr. Lynn Kennedy, thank you for being a part of my graduate committee and for your valuable assis...

Introduction Systemic amyloidosis is often associated with microscopic deposits in the thyroid gland (Kennedy, Thompson and Buchanan, 1974). Far less frequently the amyloid deposits are large enough to become palpable. When this occurs, there is usually clinical or biochemical evidence of hepatic or renal involvement (Kennedy et al., 1974). A case is reported in which the initial manifestation ...

ological incubator. TERRESTRIAL BACTERIA TYPICALLY RECOVERED FROM MARS SPACECRAFT DO NOT APPEAR ABLE TO GROW UNDER SIMULATED MARTIAN CONDITIONS. Andrew C. Schuerger, Bonnie Berry, and Wayne L. Nicholson, Dept. of Plant Pathology, University of Florida, Space Life Sciences Lab, Kennedy Space Center, FL 32899; [email protected]; Dept. of Biology, Univ. of Central Florida, Orlando, FL 32...

Tina Duelund Hjortshøj,* Karen Grønskov, Alisdair R. Philp, Darryl Y. Nishimura, Adebowale Adeyemo, Charles N. Rotimi, Val C. Sheffield, Thomas Rosenberg, and Karen Brøndum-Nielsen Kennedy Center, Medical Genetics Laboratory, Glostrup, Denmark Department of Paediatrics, Howard Hughes Medical Institute, University of Iowa, Iowa City, Iowa Department of Ophthalmology, Howard Hughes Medical Instit...

In 1960, John F. Kennedy ran against Richard Nixon in an extremely close US presidential election. Kennedy, an adroit politician if ever there were one, made the ‘missile gap’ into his major campaign issue. After his successful election, this disingenuous issue was never heard from again; the gap was suddenly gone. We were recently confronted with a gap of a different nature or rather lack of o...

A. Venkatadri, S. L. Rimrodt, A. Clements, K. R. Pugh, and L. E. Cutting F.M.Kirby Center, Kennedy Krieger Institute, Baltimore, Maryland, United States, Division of Developmental Medicine, Children's Hospital of Vanderbilt, Nashville, TN, United States, Department of Cognitive Neurology, Kennedy Krieger Institute, Baltimore, Maryland, United States, Brain Sciences Institute, Johns Hopkins Univ...

a Institute for Data, Systems, and Society, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA 02139, USA b Department of Earth, Atmospheric and Planetary Sciences, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA 02139, USA c Department of Aeronautics and Astronautics, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambri...

I was introduced to neurobiology, first by Don Kennedy, a great role model as a brilliant teacher-researcher, and later by Don Wilson, the genius behind the role of central rhythm generators in behavior. Kennedy and Wilson showed how much we have to learn about brains from studying the brain and behavior of invertebrate animals. Eric Kandel, Seymour Benzer, and Sydney Brenner inspired many of u...