OBJECTIVE To report a case of a schwannoma of nasopalpebral location, occurring in a human immunodeficiency virus (HIV)-positive patient. CLINICAL PRESENTATION AND INTERVENTION A 55-year-old man presented with a nasopalpebral painless tumefaction, pneumopathy and HIV-related immunodepression after stopping combination antiretroviral therapy. Magnetic resonance imaging showed subcutaneous mass...

Kaposi´s sarcoma is a rare tumor associated with human herpes virus 8 (HHV-8) infection. Four main clinical subtypes have been described. This study reports on a form of KS in an HIV negative and immunocompetent middle-aged man. The only remarkable factor is that he has sex with other men. This form of Kaposi´s sarcoma is rare. It occurs more in younger patients than in the classic form, is lim...

To the Editor, Kaposi ́s sarcoma (KS) is a malignant neoplasm of endothelial cells with low proliferation, described by Moritz Kaposi in 1872. It is classified into four groups: endemic, reported in African regions; epidemic, which is acquired immune deficiency syndrome(AIDS)-related; classic, at first reported primarily in Ashkenazi Jews and Mediterranean peoples, indicating a genetic relations...

Kaposi’s sarcoma (KS) was first described by Hungarian dermatologist Moritz Kaposi in 1872. Kaposi first described the lesions as “idiopathic, multiple pigmented sarcoma of the skin”. Kaposi’s sarcoma is a spindle cell tumor of endothelial origin. It is commonly associated with the endothelial lining of blood vessels. In the early 1980’s, KS was commonly associated with the AIDS epidemic. Four ...

Isolated pleural involvement is rare in Kaposi sarcoma (KS). We report an unusual case of bloody pleural effusion and ascites associated with KS in a kidney transplant recipient. A 50-year-old man who had received kidney transplantation from a living unrelated donor presented with a massive left-side pleural effusion, ascites, and a skin lesion. The pleural effusion and ascites were bloody. The...

Kaposi sarcoma herpesvirus (KSHV), a human gammaherpesvirus, is the etiological agent for the endothelial-derived Kaposi sarcoma (KS) and also for certain lymphoproliferative disorders. In these lymphoproliferations, the KSHV-infected cells carry the stigmata of B lymphocytes, with plasmablastic features. The JCI has published three manuscripts addressing key questions related to B cell infecti...

Kaposi sarcoma-associated herpesvirus (KSHV) is a recently discovered and characterized member of the herpesvirus family. It is one of a few viruses proved to be associated with tumorigenesis in humans. Its causal association with 4 clinical and epidemiologic variants of Kaposi sarcoma (classic, endemic, iatrogenic, and acquired immunodeficiency virus-associated) as well as with several lymphop...

Kaposi sarcoma (KS) is a debilitating, disfiguring and often fatal disease. The tumor is always associated with Kaposi sarcoma herpesvirus (KSHV, also known as HHV8) [1]. It is often, perhaps always, associated with immune deficiency. In transplant recipients KS is associated with pharmacologic immunosuppression, while in HIV patients KS is associated with low CD4 T cell counts. Improvement in ...

To determine the presence of Kaposi sarcoma-associated herpesvirus (KSHV) and other serologic markers, we tested serum specimens of 339 Amerindians, 181 rural non-Amerindians, and 1,133 urban blood donors (13 Amerindians) in the Brazilian Amazon. High KSHV seroprevalence in children and inverse association with herpes simplex virus type 2 indicates predominant nonsexual transmission among Ameri...