نتایج جستجو برای: kai1
تعداد نتایج: 194 فیلتر نتایج به سال:
Protein-protein interactions (PPIs) are the foundation of a plethora cellular functions ranging from DNA replication to signal transduction and cell migration, processes that often dysregulated in disease. Therefore, it is not surprising they much sought after targets treatment diseases including cancer infectious neurodegenerative diseases. PPIs take place through interfaces large area, relati...
PURPOSE KAI1 COOH-terminal interacting tetraspanin (KITENIN) has been found to act as a promoter of metastasis in murine models of colon cancer and squamous cell carcinoma (SCC). The suppression of tumor progression and metastasis of established colon cancer in mice was observed after intravenous delivery of small interfering RNA (siRNA) targeting KITENIN. The purpose of this study was to inves...
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