Rhinoscleroma is a chronic granulomatous infection of the upper airways caused by the bacterium Klebsiella pneumoniae subsp. rhinoscleromatis. The disease is endemic in tropical and subtropical areas, but its diagnosis remains difficult. As a consequence, and despite available antibiotherapy, some patients evolve advanced stages that can lead to disfiguration, severe respiratory impairment and ...

Three lectures on elliptic surfaces and curves of high rank Noam D. Elkies Over the past two years we have improved several of the (Mordell–Weil) rank records for elliptic curves over Q and nonconstant elliptic curves over Q(t). For example, we found the first example of a curve E/Q with 28 independent points P i ∈ E(Q) (the previous record was 24, by R. Martin and W. McMillen 2000), and the fi...

PURPOSE Based on the knowledge that limbal epithelial stem cells (SCs) do not express keratin-3 (K3), connexin (Cx)43, and Cx50, a study was conducted to investigate amniotic membrane (AM) culturing conditions that promote limbal SC expansion. METHODS Human limbal epithelium was expanded on intact and epithelially denuded AM, with or without a 3T3 feeder layer, and subsequently transplanted t...

Formation of parametric images requires voxel-by-voxel estimation of rate constants, a process sensitive to noise and computationally demanding. A model-based clustering method for a two-parameter model (CAKS) was extended to the FDG three-parameter model. The concept was to average voxels with similar kinetic signatures to reduce noise. Voxel kinetics were categorized by the first two principa...

Respiratory resistance (Rrs) was measured by the forced oscillation technique at 10, 20 and 30 Hz in 54 healthy subjects. The sinusoidal pressure oscillations were applied around the head, rather than at the mouth, so as to minimize transmural pressure across extrathoracic airway walls and the corresponding artefact (Peslin et al., J Appl Physiol, 1985, 59, 1790-1795). The flow (V') and volume ...

Let X be a K3 surface which is intersection of three (i.e. a net P) of quadrics in P. The curve of degenerate quadrics has degree 6 and defines a natural double covering of P ramified in this curve which is again a K3. This is a classical example of a correspondence between K3 surfaces which is related with moduli of sheaves on K3’s studied by Mukai. When general (for fixed Picard lattices) X a...

A long-standing question in the theory of rational points of algebraic surfaces is whether a K3 surface X over a number field K acquires a Zariski-dense set of L-rational points over some finite extension L/K. In this case, we say X has potential density of rational points. In case XC has Picard rank greater than 1, Bogomolov and Tschinkel [2] have shown in many cases that X has potential densi...

Protein misfolding and aggregation have been associated with several human diseases such as Alzheimer's, Parkinson's and familial amyloid polyneuropathy etc. In this study, anti-fibrillation activity of vitamin k3 and its effect on the kinetics of amyloid formation of hen egg white lysozyme (HEWL) and Aβ-42 peptide were investigated. Here, in combination with Thioflavin T (ThT) fluorescence ass...

The endomorphism algebra of a K3 type Hodge structure is a totally real field or a CM field. In this paper we give a low brow introduction to the case of a totally real field. We give existence results for the Hodge structures, for their polarizations and for certain K3 surfaces. We consider the Kuga Satake variety of these Hodge structures and we discuss some examples. Finally we indicate vari...

We discuss the geometry of the genus one fibrations associated to an elliptic fibration on a K3 surface. We show that the two-torsion subgroup of the Brauer group of a general elliptic fibration is naturally isomorphic to the two-torsion of the Jacobian of a curve associated to the fibration. We remark that this is related to Recillas’ trigonal construction. Finally we discuss the two-torsion i...