Mutually exclusive expression within the var gene family of the malaria parasite Plasmodium falciparum is important for parasite survival and virulence. In this issue of Cell, Duraisingh et al. and Freitas-Junior et al. provide evidence for the role of Sir2-dependent alterations in chromatin structure and changes in subnuclear chromatin localization in regulating var gene expression (Duraisingh...

The status of two doubtful fish species is reviewed. Percis punctata Cuvier, 1829 is confirmed to be a valid species of Parapercis Bleeker, 1863 and a senior synonym of Parapercis guezei Fourmanoir, 1966. A redescription of Parapercis punctata is provided, based on four specimens collected from the western Indian Ocean. Examination of the holotype of Neosillago marmorata Castelnau, 1875 reveale...

1 Dr K Shilpa, MBBS,MD (DVL), Assistant Professor 2 Dr B Leelavathy, MBBS, MD(DVL), Professor and Head 3 Dr K Kavya, MD, Junior Resident 4 Dr DV Lakshmi, DVD, Junior Resident 5 Dr G Divya, MBBS,MD(DVL), Senior Resident Department of Dermatology, Venereology, Leprology, Bangalore Medical College and Research Institute, Bangalore. KR Market, Bengaluru-560002, Karnataka, India Corresponding author...

Ashwani Sethi1 Deepika Sareen2 Sumit Mrig3 A.K.Agarwal4 1M.S.; Senior resident, Department of ENT; M.A.M.C. and associated L.N. Hospital 2M.B.B.S.; Junior resident, Department of ENT; M.A.M.C. and associated L.N.Hospital. 3M.B.B.S.; Junior resident, Department of ENT; M.A.M.C. and associated L.N.Hospital 4M.S.; Director Professor, Department of ENT &Dean, M.A.M.C. and associated L.N.Hospital Fr...

We present a method for pricing structured CAT bonds based on utility indifference pricing. The CAT bond considered here is issued in two distinct notes called tranches, specifically senior and junior tranches each with its own payment schedule. Our contributions to the literature of CAT bond pricing are two-fold. First, we apply indifference pricing to structured CAT bonds. We find a price for...

For teachers of medical ethics and law, teaching junior doctors is particularly interesting for a number of reasons. First, it reveals starkly the variability in ethical knowledge among doctors. One junior doctor may see no ethical or legal issue in a presented case while another will immediately identify three or four such problems. Second, once the issues are recognised, most junior doctors a...

This paper presents outcomes from a cognitive engineering project addressing the design problems of computerised monitoring in neonatal intensive care. Cognitive engineering is viewed, in this project, as a symbiosis between cognitive science and design practice. A range of methodologies has been used: interviews with neonatal staff, ward observations, and experimental techniques. The results o...

M-learning is an important role in e-learning environment by mobile device. However, in Taiwan junior high education, few research was to develop an m-learning system on the geography curriculum. Geography courses are quite indispensable. The sense of direction of training is one of the first studies in Taiwan junior high education of geography curriculum; however, many students’ sense of direc...

Examined the roles of gender, instrumentality, and expressivity as moderator of the relations between stressful events and psychological symptoms in samples of junior high (n = 93), senior high (n = 140), and college students (n = 145). Female adolescents in all three samples reported more overall negative events than did males. Females in the junior and senior high samples reported more negati...

This study examines whether contrived success on a task closely related to school subjects would promote students’ self-efficacy. In our previous study, junior high school students who experienced contrived success on anagram tasks raised their sense of self-efficacy and kept it high for a year. We tried to replicate that study, substituting calculation tasks for the anagrams. One hundred eight...