نتایج جستجو برای: jia
تعداد نتایج: 3259 فیلتر نتایج به سال:
Juvenile idiopathic arthritis (JIA) is a disease characterized by chronic joint inflammation, caused by a deregulated immune response. In patients with JIA, heat shock proteins (HSPs) are highly expressed in the synovial lining tissues of inflamed joints. HSPs are endogenous proteins that are expressed upon cellular stress and are able to modulate immune responses. In this review, we concentrat...
This paper investigates the hybrid chaos synchronization of identical 4-D hyperchaotic Qi systems, 4-D identical hyperchaotic Jia systems and hybrid synchronization of 4-D hyperchaotic Qi and Jia systems. The hyperchaotic Qi system (2008) and hyperchaotic Jia system (2007) are important models of hyperchaotic systems. Hybrid synchronization of the 4-dimensional hyperchaotic systems addressed in...
BACKGROUND Few prospective data have been published on the comparison of bone density and quality in homogeneous groups of patients with juvenile systemic lupus erythematosus (JSLE) and juvenile idiopathic arthritis (JIA). OBJECTIVE AND HYPOTHESIS The objective of this study is to perform a longitudinal evaluation of the prevalence and the characteristics of bone mass and quality and to evalu...
BACKGROUND Our intent was to identify differences between the transcriptome of fibroblast-like synoviocytes (FLS) in oligoarticular juvenile idiopathic arthritis (JIA) before extension when compared to persistent subtype of JIA, when the two are clinically indistinguishable. Additionally, we sought to determine if differences between the transcriptomes of FLS from extended-to-be and polyarticul...
OBJECTIVE Systemic juvenile idiopathic arthritis (JIA) is characterized by fevers, rash, and arthritis, for which interleukin-1 (IL-1) and IL-6 inhibitors appear to be effective treatments. Pulmonary arterial hypertension (PAH), interstitial lung disease (ILD), and alveolar proteinosis (AP) have recently been reported with increased frequency in systemic JIA patients. Our aim was to characteriz...
Juvenile idiopathic arthritis (JIA) is a chronic painful disorder conceivably with adverse psychological sequelae that might influence the outcome of the disease and its treatment. This study was designed to detect the presence of psychiatric disorders and associated abnormal psychosocial situations among children and adolescents with JIA and to evaluate their impact on and burden for their car...
Background: Temporomandibular joint (TMJ) arthritis is common in children with juvenile idiopathic arthritis (JIA), but often clinically asymptomatic. Magnetic resonance imaging (MRI) is the most reliable examination method, but requires sedation in young children. The aim of our study was to evaluate whether early TMJ MRI will change the treatment of patients with newly diagnosed JIA. Methods:...
Comparison of epidemiological studies of JIA is challenging due to many influencing factors, mainly differences in classification criteria or study designs (e.g. populationbased, hospital-based, questionnaires, registry data). Recently, longitudinal cohort studies have provided important contributions to the understanding of the disease course of JIA in the long run. Latest advances in research...
Methods A cohort of 1190 JIA patients enrolled in the German JIA Enbrel registry has been used for screening. Matching criteria included JIA subtype, gender, disease duration, use of corticosteroids, oligoversus polyarthritis at therapy start and the sedimentation rate. Efficacy was determined using the PedACR 30/ 50 and 70 response criteria. Safety assessments were based on adverse events repo...
Objectives Primary objective of this study was to evaluate influence of JIA subtype and duration of metotrexate (MTX) and steroids treatment on time to achieve and ability to maintain remission in JIA patients on biologic treatment. The second aim was to establish if there is contribution of tumor necrosis factor ά (TNFά–308) promoter and FokI vitamin D receptor (VDR) polymorphism on clinical o...
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