SUMO is a ubiquitin-related protein that functions as a posttranslational modification on other proteins. SUMO conjugation is essential for viability in Saccharomyces cerevisiae and is required for entry into mitosis. We have found that SUMO is attached to the septins Cdc3, Cdc11, and Shs1/Sep7 specifically during mitosis, with conjugates appearing shortly before anaphase onset and disappearing...

2. Vehicles can be designed to provide crash protection to the occu little or no penalty to the weight and cost of the vehicle. 3. Vehicle crashworthiness can be improved by providing the principles to designers and by emphasizing the importance of this design responsibility. Decisions and design choices can then be · and in cases where two or more comparable choices are possible, the in favor ...

SUMOylation contributes to the regulation of many essential cellular factors. Diverse techniques have been used to explore the functional consequences of protein SUMOylation. Most approaches consider the identification of sequences on substrates, adaptors, or receptors regulating the SUMO conjugation, recognition, or deconjugation. The large majority of the studied SUMOylated proteins contain t...

Concentrations of nitrogen dioxide (NO(2)), sulfur dioxide (SO(2)), ozone (O(3)), and ammonia (NH(3)) were determined in the ambient air of Al-Ain city over a year using the passive sampling method associated with ion chromatographic and potentiometric detections. IVL samplers were used for collecting nitrogen and sulfur dioxides whereas Ogawa samplers were used for collecting ozone and ammonia...

A new simple and highly sensitive spectrophotometric method for determining nitrogen dioxide in air was developed. The method is based on converting atmospheric nitrogen dioxide to nitrite ions within the IVL passive samplers used for samples collection. Acidifying nitrite ions with concentrated HCl produced the peroxynitrous acid oxidizing agent which was measured using 2, 2-azino-bis(3-ethyl ...

Alignment of amino acid sequences from various acyltransferases [sn-glycerol-3-phosphate acyltransferase (GPAT), lysophosphatidic acid acyltransferase (LPAAT), acyl-CoA:dihydroxyacetone-phosphate acyltransferase (DHAPAT), 2-acylglycerophosphatidylethanolamine acyltransferase (LPEAT)] reveals four regions of strong homology, which we have labeled blocks I-IV. The consensus sequence for each cons...

W e cons ide r the s imple cub ic la t t ice Z J in d d imens ions , to each of w h o s e sites x ~ Z J we ass ign a spin va r i ab le wi th va lues Sx e R. Le t A, V,... c Z d d e n o t e finite cubes wi th cen te r at the o r ig in of the lat t ice. A c o n f i g u r a t i o n S v = { S ~ ; x e V} in V is an e l e m e n t of R Ivl, where Irl is the n u m b e r of sites in V. T h e ene rgy for...

A major obstacle to putting software verification research into practice is the high cost of developing the infrastructure enabling the application of verification algorithms to actual production code, in all of its complexity. Handling an entire programming language is a huge endeavor that few researchers are willing to undertake; even fewer could invest the effort to implement a verification ...

Nucleic Acids Research Sequence of a cDNA coding for human IRF-2 Susumu Itoh*, Hisashi Harada, Takashi Fujita, Tsutomu Mimura and Tadatsugu Taniguchi Institute for Molecular and Cellular Biology, Osaka University, Yamadaoka 1-3, Suita-Shi, Osaka 565 and 'Faculty of Pharmaceutical Science, Osaka University, Yamadaoka 1-6, Suita-shi, Osaka 565, Japan Submitted September II, 1989 EMBL accession no...

The chemistry leading to the selective potentiometric response toward salicylate of polymer membranes doped with 5,10,15,20-tetraphenyl(porphyrinato)tin(IVl dichloride (Sn(TPPlCls) is examined via ‘19Sn NMR, 3H,0 uptake, spectrophotometric, and solution conductometric techniques. The response properties of ion-selective electrodes prepared with such membranes suggest a complex mechanism of anio...