INTRODUCTION Sperm chromatin integrity assessment has been suggested as a fertility predictor. The aim of this study was to examine the relationship between the results of sperm chromatin structure assay (SCSA) and the outcome of IVF, ICSI and intrauterine insemination (IUI). METHODS A total of 306 consecutive couples undergoing assisted reproduction were included. IUI was performed in 131, I...

BACKGROUND To evaluate the impact of the association of endometrioma with or without deep infiltrating endometriosis (DIE) after a first intra cytoplasmic sperm injection- in vitro fertilization (ICSI-IVF) cycle on pregnancy rate. MATERIALS AND METHODS In this retrospective study, women with endometrioma who underwent a first ICSI-IVF cycle from January 2007 to June 2010 were reviewed for pre...

OBJECTIVE Compare the efficacy of surrogate or gestational carrier (GC) cycles to that of autologous in vitro fertilization (IVF)/intracytoplasmic sperm injections (ICSI) in patients with gynecologic or medical co-morbidities contraindicative to pregnancy. DESIGN Retrospective cohort study. SETTING Infertility patients from a single university hospital-based program from 1998-2009. INTERV...

BACKGROUND To study the effect of metformin before and during assisted reproductive technology (ART) on the clinical pregnancy rate (CPR) in non-obese women with polycystic ovary syndrome (PCOS). METHODS A multi-centre, prospective, randomized, double-blind study was conducted in eight IVF clinics in four Nordic countries. We enrolled 150 PCOS women with a body mass index <28 kg/m(2), and tre...

BACKGROUND Evidence from animal studies suggests that exposure to organophosphate flame retardants (PFRs) can disrupt endocrine function and impair embryo development. However, no epidemiologic studies have been conducted to evaluate effects on fertility and pregnancy outcomes. OBJECTIVES We evaluated associations between urinary concentrations of PFR metabolites and outcomes of in vitro fert...

IVF success rates are low, with approximately one-third of all cycles resulting in live births1. Improving IVF success rates would make a significant difference in the lives of many women trying to conceive. Chromosome aneuploidy (abnormal number of chromosomes) is a major cause of IVF failure, miscarriage, and, in rare cases, abnormal pregnancy and live birth. Most aneuploidies arise during th...

BACKGROUND Tubal disease, and particularly hydrosalpinx, has a detrimental effect on the outcome of in-vitro fertilisation (IVF). It has been less clear whether surgical intervention for tubal disease prior to IVF is effective in improving the likelihood of successful outcome. Most data are retrospective or poorly controlled. To date no single prospective randomised trial has shown a significan...

OBJECTIVE Evaluation of the impact of agonist or antagonist protocol selection on pregnancy outcomes after failure of in-vitro fertilization (IVF) treatment cycles which were down regulated with Gonadotropin Releasing Hormone (GnRH) agonist. MATERIALS AND METHODS This was a retrospective study. Two hundred and sixty nine patients who were treated with GnRH agonist protocol between years 2002-...

ObjectiveTo compare obstetric and perinatal outcomes between pregnancies conceived using in vitro fertilization (IVF) natural of the same women.DesignThis was a case-control study deliveries November 2008 January 2020 which each IVF pregnancy matched to woman (1:1 ratio).SettingUniversity hospital.Patient(s)We included women with consecutive live singleton (>24 weeks gestation) at Edith Wolfson...

The purpose of this study was to investigate risk factors that are associated with heterotopic pregnancy (HP) following in vitro fertilization (IVF)-embryo transfer (ET) and to demonstrate the outcomes of HP after the surgical treatment of ectopic pregnancies. Forty-eight patients from a single center, who were diagnosed with HP between 1998 and 2012 were included. All of the patients had recei...