Although human herpesvirus 8 (HHV-8) is the etiologic agent of Kaposi sarcoma (KS), there are no formal guidelines for the clinical management of HHV-8 infection. In patients infected with human immunodeficiency virus (HIV), highly active antiretroviral therapy (HAART) is the best tool for the prevention of KS. In patients who have undergone transplantation, KS is often managed by curtailing im...

According to professional journals, Internet information services and consultants, RFID (Radio Frequency Identification) seems to be “the new technology hype” which “will revolutionise business performance across supply chains” (Accenture). While low-frequency RFID has been used in some areas in the industrial world for more than a decade (source), the recent decision by Wal-Mart and the U.S. D...

Joint disease commonly results in severe weakness of associated muscles. Efforts to restore strength are often unsuccessful, even in the absence of pain. This is because of the underlying inhibition of motoneurones by afferent signals from in and around the affected joint, 'arthrogenous inhibition'. This phenomenon has received scant scientific attention, but several experimental techniques are...

Darwin’s recognition that male–male competition and female choice could favor the evolution of exaggerated male traits detrimental to survival set the stage for more than a century of theoretical and empirical work on sexual selection. While this Darwinian paradigm represents one of the most profound insights in biology, its preoccupation with sexual selection as a directional evolutionary forc...

Illustration by Lisa Haney Technically savvy professionals often come up with good ideas that could be of value to firms and to other individuals. With a little luck, funding, and hard work, the better of these ideas can lead to successful new firms or perhaps even entirely new industries. Moving an idea past development and into the market incurs so many roadblocks that the entrepreneur who at...

Migraine often runs in families and is associated with both genetic and environmental factors. Clinical and genetic heterogeneity as well as the influence of environmental factors have hampered the identification of the gene responsible for migraine disorder. Family/twin studies suggest the presence of hereditary susceptibility. Several different types of mutations or association studies with g...

Lipid lowering treatment is of benefit in the prevention of coronary heart diseases (CHD) and other vascular events. So far many studies have been carried out to prove the safety, efficacy and beneficial effects of lipid-lowering treatment in various countries. These studies can be categorized into two groups: (1) studies done to prove the effectiveness of lipid lowering treatment in the primar...

The trend toward globalisation of products and services has brought a strong economic imperative to the development of general methods for the localisation of software to different cultural environments. While ad hoc, bolt-on localisation may satisfy immediate commercial objectives, its extension to multiple locales is not cost-effective and an integrated strategy is needed. In this more sustai...