The effects of temperature on various aspects of neural activity from single cell to neural circuit level have long been known. However, how temperature affects the system-level of activity typical of experiments using non-invasive imaging techniques, such as magnetic brain imaging of electroencephalography, where neither its direct measurement nor its manipulation are possible, is essentially ...

HINDRIK MULDER,1,2 SAMUEL GEBRE-MEDHIN,3,4 CHRISTER BETSHOLTZ,4 FRANK SUNDLER,2 AND BO AHRÉN5 1Section for Molecular Signaling, Department of Cell and Molecular Biology, Lund University, SE-221 00 Lund; 2Section for Neuroendocrine Cell Biology, Department of Physiological Sciences, Lund University, SE-221 85 Lund; 3Section for Molecular and Cellular Physiology, Department of Physiological Scien...

Though IT usage has been identified as a significant construct, significant gaps remain in our understanding of how IT is used by different organizational members. In this paper, we examine the key organizational, external environmental, and IT-related factors that influence IT usage in organizations across management and non-management levels. Based on data from over 500 functional managers, w...

Environmental enrichment has become increasingly utilized in rodent models of aging and neurodegenerative disease in order to prevent or reverse cognitive decline and neuronal dysfunction. However, the potential application of this body of work to human cognitive aging has rarely been discussed. The present article provides an overview of the rodent research that has tested the effects of envir...

Postextrasystolic potentiation (PESP), the increase in contractility that follows an extrasystole, is an interesting phenomenon that has been known for almost 100 years. The literature on this effect is reviewed. It is found that there is significant evidence that the phenomenon is independent of muscle loading and represents a distinct property of the myocardium. Examination of the literature ...

The terms professionalism and humanism are sometimes confused as being synonymous; even more confusing, each is sometimes regarded as a component feature of the other. The author argues that, in the context of medicine, the two terms describe distinctly different, albeit intimately linked attributes of the good doctor. Professionalism denotes a way of behaving in accordance with certain normati...

Postextrasystolic potentiation (PESP), the increase in contractility that follows an extrasystole, is an interesting phenomenon that has been known for almost 100 years. The literature on this effect is reviewed. It is found that there is significant evidence that the phenomenon is independent of muscle loading and represents a distinct property of the myocardium. Examination of the literature ...

Now that biologic therapy has been used for some years in the treatment of psoriasis and we anticipate short and medium term outcomes consistent with the results of the pivotal clinical trials, the objective of the dermatologist with experience in managing this condition has changed. We now look beyond the predicted response to weigh up the likelihood that a given drug which achieves a satisfac...