The antithrombogenic endothelial cell defense (ATECD) describes the properties that enable the endothelium to prevent circulating blood platelets from adhering to, or aggregating on, the vascular wall. ATECD was investigated in an experimental model in which bovine passage 0 cultured endothelial cells (EC) were incubated with aggregating platelets and autologous plasma in a computer-operated ag...

In the title complex, bis-{μ-1-[(1H-benzimidazol-1-yl)meth-yl]-1H-1,2,4-triazole}disilver(I) dinitrate, [Ag(2)(C(10)H(9)N(5))(2)](NO(3))(2), the Ag(I) ion is nearly linearly coordinated [N-Ag-N angle is 155.72 (14)°] by two 1-[(1H-benzimidazole-1-yl)meth-yl]-1H-1,2,4-triazole (bmt) ligands. In addition, two bmt ligands link two Ag(I) ions, forming a dinuclear unit with an Ag⋯Ag distance of 5.01...

In the title compound, [Cu(C(16)H(20)N(2)S(2))(H(2)O)](NO(3))(2)·CH(3)CN, the Cu(II) atom displays a distorted square-pyramidal coordination, in which a water mol-ecule occupies the apical position and the basal plane is formed by two N atoms and two S atoms of a 1,8-bis-(pyridin-2-yl)-3,6-dithia-octane ligand. The crystal packing is stabilized by O-H⋯O and C-H⋯O hydrogen bonds.

The title compound, cis-diacetonitrile[(1R,2R)-1,2-diaminocyclohexane-κ(2)N,N']platinum(II) dinitrate monohydrate, [Pt(C(2)H(3)N)(2)(C(6)H(14)N(2))](NO(3))(2)·H(2)O, is a molecular salt of the diaminocyclohexane-Pt complex cation. There are two formula units in the asymmetric unit. Apart from the two charge-balancing nitrate anions, one neutral molecule of water is present. The components inter...

This paper describes a series of four conversation tests, which were carried out in order to assess speech quality under degradations occurring in combined PSTN/ISDN/VoIP networks. Based on the test results, the validity of predictions by the model currently recommended by the ITU-T for network planning (the E-model, [1]) is discussed.

BACKGROUND Aerobic exercise enhances endothelium-dependent vasodilation in hypertensive patients, patients with chronic heart failure, and healthy individuals. However, it is unclear how the intensity of exercise affects endothelial function in humans. The purpose of the present study was to determine the effects of different intensities of exercise on endothelium-dependent vasodilation in huma...

OBJECTIVE The vasomotor responses of the epicardial coronary arteries to acetylcholine were examined in patients with normal coronary arteries and chest pain. DESIGN Quantitative angiography was used to measure minimum lumen diameter of proximal and distal coronary artery segments at baseline, during intracoronary infusion of acetylcholine (10(-7) - 10(-3) mol/l), and following an intracorona...

To compare two-dimensional (2-D) echocardiographic estimates of right ventricular size and performance to similar determinations from equilibrium radionuclide angiography (RNA) before and after isosorbide dinitrate, we evaluated 19 patients with severe chronic obstructive pulmonary disease. The end-diastolic and end-systolic volumes estimated from subcostal 2-D echocardiographic views of the ri...

BACKGROUND Guidelines for heart failure (HF) recommend prescription of guideline-directed medical therapy before hospital discharge; some of these therapies are included in publicly reported performance measures. The burden of new medications for individual patients has not been described. METHODS AND RESULTS We used Get With The Guidelines-HF registry data from 2008 to 2013 to characterize p...

The effect of isosorbide dinitrate (ISDN), 5 mg sublingually, on the diameters of coronary artery stenoses (n = 27) was examined in 20 patients. Another 18 patients with angiographically normal coronary arteries received the same amount of ISDN and were used as controls. Prestenotic and stenotic diameters were measured with a vernier calliper having an accuracy of 0.05 mm. The degree of stenosi...