Health technology The study focused on the use of two conduit vasodilators in the prevention of arterial conduit spasm after coronary bypass grafting (CABG). Patients received a 24-hour intravenous infusion of either nitroglycerin (0.1 microgram.kg-1.min-1) or diltiazem (0.1 mg/kg during 20 minutes and then 0.1 mg.kg-1.min-1), followed by 6 months of treatment with a daily dose of isosorbide mo...

• New tools for chiral voltammetry in ionic liquid media: molecular “tweezers” Tweezer chirality from isomannide/isosorbide cores derived pool arm design enables modulating redox properties and coordination modes Tweezers can be liquids or/and additives achiral Successful enantiodiscrimination CV tests with tweezer Ionic (ILs), either themselves (CILs) or modified small quantities of CILs relat...

The efficacy of orally administered isosorbide dinitrate (IS) has been questioned. Recently vasodilators have been shown to lower left ventricular filling pressure (LVFP) and raise cardiac output in heart failure. In the present study oral IS was evaluated in 12 patients with high LVFP due to heart failure. After right heart catheterization, patients with LVFP > 14 mm Hg were randomized double-...