RATIONALE Associations between oligomeric isocyanate exposure, sensitization, and respiratory disease have received little attention, despite the extensive use of isocyanate oligomers. OBJECTIVES To investigate exposure-response relationships of respiratory symptoms and sensitization in a large population occupationally exposed to isocyanate oligomers during spray painting. METHODS The prev...

PURPOSE Early recognition improves the prognosis of isocyanate asthma. A major unanswered question is whether IgE-dependent mechanisms are of diagnostic value? Our objective was to appraise serological methods using various methylenediphenyl diisocyanate (MDI)-albumin conjugates and weigh up the data versus the outcome of standardized comprehensive clinical diagnostics to evaluate the viability...

Waterborne isocyanate-free grafted poly(hydroxy urethane)-poly(butyl methacrylate) hybrid dispersions were synthesized by miniemulsion polymerization. Grafting was induced including methacrylate functionalities in the urethane) and controlled degree of functionalization. It is shown that grafting enabled a fine tuning mechanical properties PHU containing hybrids.

this research was conducted to investigate the effect of acetylation and type of resin on fire resistance of one and three layered populus particleboard. populus particles were acetylated at three levels of acetyl content (wpg of 0, 8.39% and 17.27%). in manufacturing of one and three layered boards with acetylated particles in all thickness or surface of the boards two type of resin, urea form...

Although the antitumor effects of chloroethylnitrosoureas have been shown to be due primarily to DNA-DNA cross-linking by the alkylating moieties of these agents, the basis of the often accompanying bone marrow toxicity has been more controver sial. We report on the relative bone marrow toxicity of four model nitrosoureas with different alkylating and Carbamoylating activi ties: 1,3-bis(2-chlor...

The determination of isocyanates concentrations in air is complicated by thepresence of these substances as monomers and oligomers as well as in thevapor and aerosol phases. Direct-reading instruments (DRIs) are available fordetermining the diisocyanate concentrations in workplace air, but they arecalibrated for the monomers only. Industry uses polymeric diisocyanateswhich c...

December 3, 1984 marks one of the deadliest chemical disasters of the world took place in Bhopal. The disaster took a toll of 3600 human lives and scores of pets almost instantly. Additional 200 000 people were exposed to the killer gas—methyl isocyanate and its intermediates—to varying degrees.1 Almost 27 years have gone by since occurrence of this tragic event, the health status of the affect...