A new atropine drug-FET sensor, which was made of an ISFET (ion sensitive field effect transistor) and a drug sensitive membrane prepared by adding electric active matter to a β-cyclodextrin solution, was developed. The pH influence, selectivity, response curve, reproducibility, stability, response time and life of this sensor were investigated. A preliminary application of the sensor was discu...

Monitoring the bioelectrochemical activity of living cells with sensor array-based microsystems represents an emerging technique in a large area of biomedical applications, ranging from basic research to various fields of pharmacological analyses. The main appeal is the ability of these miniaturised microsystems to perform, in real time, non-invasive in-vitro investigations of the physiological...

A new configuration realizing water quality monitoring device using ISFET involving CMOS differential voltage current conveyor (DVCC) based low pass filter free from trans-conductance variation using Low-voltage PMOS bulkdriven cascade current mirror (P MOS BDCCM) current mirrors is proposed. The circuit uses four DVCCs as active elements and together with two capacitors and five resistors as p...

This work presents a multiparametric system capable of characterizing and classifying white wines according to the grape variety and geographical origin. Besides, it quantifies specific parameters of interest for quality control in wine. The system, known as a hybrid electronic tongue, consists of an array of electrochemical microsensors-six ISFET based sensors, a conductivity sensor, a redox p...

We have demonstrated a chip-based diagnostics tool for the quantification of metabolites, using specific enzymes, to study enzyme kinetics and calculate the Michaelis-Menten constant. An array of 256×256 ion-sensitive field effect transistors (ISFETs) fabricated in a complementary metal oxide semiconductor (CMOS) process is used for this prototype. We have used hexokinase enzyme reaction on the...

This paper describes the design, modeling, and experimental characterization of an electrochemical sensor array for on-line monitoring of fermentor conditions in both miniaturized cell assays and in industrial scale fermentations. The viable biomass concentration is determined from impedance spectroscopy. As a miniaturized electrode configuration with high cell constant is applied, the spectral...