Introduction: Postoperative, lingual swelling and necrosis are unusual complications that can lead to life-threatening airway obstruction. We report a case of bilateral ischemic necrosis of the tongue following transoral neurosurgical procedure. Observation: A Davis-Boyle mouth gag was used for tumor exposition and the operation lasted 8 h. At the end of the surgery, we noticed a bluish discolo...

Ischemic stroke occurs under a variety of clinical conditions and has different pathogeneses, resulting in necrosis brain parenchyma. Stroke pathogenesis is characterized by neuroinflammation endothelial dysfunction. Some the main processes triggered early stages ischemic damage are rapid activation resident inflammatory cells (microglia, astrocytes cells), cytokines, translocation intercellula...

Histologic examination of the structure traumatic osteomyelitic foci in acute and chronic stages, types bone tissue lesions was performed experimental morphologic clinical biopsy material. Differences various inflammatory changes rates patients groups were statistically determined. In stage focus showed centrally located necrosis exudate surrounded by internal, fibrous osseous membranes capsule...

12. Torvik A, Svindland A: Is there nerve cell loss in the surroundings of brain infarcts? The penumbra zone. Acta Neurol Scand, in press 13. MetterEJ.MazziottaJC, Itabashi HH, MankovichNJ, PhelpsME, 17. Kuhl DE: Comparison of glucose metabolism, x-ray CT, and postmortem data in a patient with multiple cerebral infarcts. Neurology 35: 1695-1701, 1985 14. Lassen NA, Olsen TS, H0jgaard K, Skriver...

The purpose of this study was to use cardiac MRI to define the morphology of the reversibly injured peri-infarct border zone in patients treated with primary percutaneous coronary intervention (PPCI) for acute ST elevation myocardial infarction. In 15 patients, T2-weighted myocardial edema imaging was used to identify the ischemic bed or area at risk (AAR), and late gadolinium enhancement imagi...

Arteriosclerotic vascular disease is the most common cause of death and a major cause of disability in the developed world. Adverse outcomes of arteriosclerotic vascular disease are related to consequences of tissue ischemia and necrosis affecting the heart, brain, limbs, and other organs. Collateral artery growth or arteriogenesis occurs naturally and can help restore perfusion to ischemic tis...

OBJECTIVE To assess the implication of tumor necrosis factor alpha (TNF-alpha) and interleukine-6 (IL-6) in acute ischemic stroke and to correlate this with lesion size, vascular risk factors, and neurological impairment. METHODS We included 70 patients consecutively admitted to the Department of 1st Neurology, Haydarpasa Numune Educational and Research Hospital, Istanbul, Turkey, between Sep...

Having recently described the injurious role of caspase-1-mediated production of the proinflammatory cytokine IL-18 in ischemic acute renal failure (ARF), we report here on the effect of the newly developed caspase inhibitor Quinoline-Val-Asp(Ome)-CH(2)-OPH (OPH-001) on caspase-1, IL-18, neutrophil infiltration, and renal function in ischemic ARF. C57BL/6 mice with ischemic ARF treated with OPH...

BACKGROUND To establish a relation between the survival rate of island skin flaps submitted to prolonged ischemia and the effect of streptokinase and allopurinol administered after the ischemic period. METHODS A total of 48 male Winstar rats, each weighing between 300 and 350 grams,were separated into four groups of twelve as follows: control, allopurinol, streptokinase and association of all...