Vitamin D deficiency is associated with cardiovascular and metabolic diseases. Cardiovascular diseases, in turn, are responsible for mortality of patients with type 2 diabetes (T2D). We investigated whether a single parenteral dose of 25(OH) Vit D could improve the endothelial function in T2D patients with ischemic heart disease. A randomized, placebo-controlled, and double-blind trial was perf...

Major heart diseases such as ischemia and hypertrophic myocardiopathy are accompanied with significant changes in the passive mechanical properties and active contractility of myocardium. Identification of these changes helps diagnose heart diseases, monitor therapy, and design surgery. A dynamic cardiac elastography (DCE) framework is developed to assess the anisotropic viscoelastic passive pr...

Ischemic cardiac diseases are the leading causes of mortality in the developed and developing regions of the world. Although vascular problems may accompany coronary artery disease, association of primary cardiac tumors with ischemic heart disease and the treatment of the combination are rarely reported in the literature. This report presents a male patient who successfully underwent concomitan...

background: ischemic heart disease (ihd) is the main cause of morbidity and mortality worldwide, and a considerable part of these patients attend to emergency departments, which increases the burden to these busy departments. the aim of this study was to develop a prediction model enabling prediction of all cause emergency department (ed) visits in patients with documented coronary stenosis in ...

Mildronate (3-(2,2,2-trimethylhydrazine)propionate; THP; MET-88; meldonium, quaterine) is an anti-ischemic drug developed in the Latvian Institute of Organic Synthesis. Mildronate was designed as a promising inhibitor of carnitine biosynthesis aimed to prevent accumulation of cytotoxic intermediate products of fatty acid betaoxidation in ischemic tissues and to block this highly oxygenconsuming...

Ischemic heart disease, resulting from ischemic and anoxic cardiomyocytes, can lead to the abnormal metabolic activity which is able result in some serious diseases including cardiac failure, thrombus other deadly disease it also bad factor health of human. Besides, oxidative stress one most factors this destroy healthy tissue, protein so on. Hypoxia, as a signal, launch hypoxia-inducible 1-alp...

Congenital anomalies and within them anatomical variations of coronary arteries, although uncommon, are being increasingly studied diagnosed due to the close relationship symptoms such as angina, dyspnea, syncope or arrhythmias in young people without comorbidities. This study aimed present case report a patient with ischemic secondary malformation artery. We describe moment admission, diagnosi...

Since the discovery of Helicobacter pylory (H. pylori), several studies have been published concerning a hypothetical role of this bacterium in different extragastric diseases, such as ischemic heart disease, idiopathic thrombocytopenic purpura, iron deficiency anemia or other disorders. The majority of those studies may be classified as epidemiological or eradicating trials but there are also ...