BACKGROUND Calcium inhibits and ascorbic acid (AA) enhances iron absorption from iron-fortified foods. Absorption efficiency depends on iron status, although the interaction is unclear. OBJECTIVE We investigated the ability of AA to overcome calcium-induced inhibition of iron absorption in children differing in iron status. METHODS The effect of calcium (0, 100, and 200 mg/test meal) on iro...

BACKGROUND Vitamin D and iron deficiencies frequently co-exist. It is now appreciated that mechanistic interactions between iron and vitamin D metabolism may underlie these associations. OBJECTIVE We examined interrelations between iron and vitamin D status and their regulatory hormones in pregnant adolescents, who are a group at risk of both suboptimal vitamin D and suboptimal iron status. ...

OBJECTIVE The aim of this study was to determine the effect of combined calcium and iron versus single iron supplementation on iron status in Bolivian schoolchildren. METHODS Children ages 6 to 10 y old (N = 195), were randomly assigned to receive either 700 mg Ca (as calcium carbonate) plus 30 mg Fe (as ferrous sulfate) (Ca + Fe group) or 30 mg Fe (as ferrous sulfate) (Fe group). The doses w...

abstract background: cut380a intra uterine device intra uterine device (iud) is used in the health system of iran. the most important and frequent side effects of the iuds are hypermenorrhea and polymenorrhea. in iran, iron supplement are not prescribed for the iud users and there are no documents indicating their iron reservation status. this study was performed to determine the iron status in...

In studies conducted in both Cambridge, Massachusetts and Guatemala (1), we have obtained data confirming our hypothesis that iron nutrition affects cognitive function in children (2, 3). The design and conduct of these studies led us to realize the great complexities involved both in the definition of nutritional status in man and in the selection of relevant measures of cognitive function. He...

BACKGROUND AND AIMS Exercise-induced iron deficiency is a common finding in endurance athletes. It has been suggested recently that hepcidin may be an important mediator in this process. OBJECTIVE To determine hepcidin levels and markers of iron status during long-term exercise training in female runners with depleted and normal iron stores. METHODS Fourteen runners were divided into two gr...

Women have lower iron stores than men because of iron loss during their reproductive years. However, variation between women could result from differences in iron loss, aspects of iron homeostasis common to men and women, or a combination of both. We compared the effects of age, menopause, menstrual blood loss and the number of pregnancies (sex-specific factors), and the effects of genetic vari...

Exercise-induced skeletal muscle microtrauma is characterized by loss of muscle cell integrity, marked aseptic inflammatory response, and oxidative stress. We examined if iron supplementation would alter redox status after eccentric exercise. In a randomized, double blind crossover study, that was conducted in two cycles, healthy adults (n = 14) and children (n = 11) received daily either 37 mg...