Iron deficiency anemia is one of the major nutritional deficiency disorders. Iron deficiency anemia occurs due to decreased absorption of iron from diet, chronic blood loss and other associated diseases. The importance of iron and deleterious effects of iron deficiency anemia are discussed briefly in this review followed by the transdermal approaches to deliver iron. Transdermal delivery of iro...

Background Since the discovery of Helicobacter pylori, several clinical reports have demonstrated that H. Pylori infection has emerged as a new cause of refractory iron stores in children. We carried out a systematic literature review to primarily evaluate the existing evidence on the association between childhood H. Pylori infection and iron deficiency anemia (IDA) and secondly, to investigat...

Yeast frataxin homolog (Yfh1) is the orthologue of human frataxin, a mitochondrial protein whose deficiency causes Friedreich Ataxia. Yfh1 deficiency activates Aft1, a transcription factor governing iron homeostasis in yeast cells. Although the mechanisms causing this activation are not completely understood, it is assumed that it may be caused by iron-sulfur deficiency. However, several eviden...

Two hundred and seventy school children between 13 to 20 years were investigated for iron deficiency. Overall iron deficiency (assessed by serum ferritin assay) was 39% in adolescents; 30% boys and 54% girls were iron depleted, anemia was found in 17% boys (Hb 13g/dl) and in 18% girls (Hb 12g/dl). Iron deficiency was more frequent than anemia in adolescent girls than boys. Iron deficient childr...

INTRODUCTION Thrombocytosis is a common disorder in patients diagnosed with iron deficiency anemia. The decreased platelet counts commonly found iron deficiency anemia is rarely reported in clinical practice. The exact mechanism of the occurrence of thrombocytopenia in iron deficiency anemia remains unclear. In this case report we discuss a triad of symptoms seen in the African American populat...

The aim of this study was to assess the prevalence of iron deficiency and iron deficiency anemia in relation to variables such as: age, weight, height, mother s education, number of family members, and nutritional habits among female elementary school children (age 6-12 years) in the western province of Saudi Arabia. A total of 123 female children were selected for this study. Complete blood co...

BACKGROUND Current markers of iron deficiency tend to be less reliable in pregnancy. OBJECTIVE Our aim was to study the usefulness of soluble serum transferrin receptor (sTfR) as a marker for iron deficiency during early and late gestation and to define iron status in 254 pregnant Swedish women. DESIGN We performed a cross-sectional and longitudinal evaluation of sTfR in comparison with con...

Iron deficiency, even in the absence of anemia, can be debilitating, and exacerbate any underlying chronic disease, leading to increased morbidity and mortality. Iron deficiency is frequently concomitant with chronic inflammatory disease; however, iron deficiency treatment is often overlooked, partially due to the heterogeneity among clinical practice guidelines. In the absence of consistent gu...

zinc is one of the elements necessary for growth and health in human. some evidences indicate that the zinc deficiency is one of real difficulties for the public health in developed and developing countries. since the pregnant women are more at risk by the zinc deficiency, and this can cause many problems, in this study we tried to find out the rate of zinc deficiency in pregnant women within t...

differential diagnosis of iron-deficiency anemia and beta-thalassemia, two common causes of anemia, affects the treatment in pregnant women. to help the diagnosis, we have tried to asses the pure effect of gestation on diagnostic criteria, eliminating iron and folate deficiency. in a prospective study, 46 thalassemic women were given ferrous sulphate tablets and folate. some indices, cbc and hb...