BACKGROUND Due to negligence, Persian (Iranian) traditional medicine has had a weak presence in the world of research for a long time. However, in recent years, a variety of activates by research and faculty centers have created awareness and a platform to introduce and promote Persian medicine to the world. The aim of this study is to present and analyze scientific achievements of Persian medi...

introduction: it is essential for clinicians to have knowledge about root canal configuration, although its morphology varies largely in different ethnicities and even in different individuals within the same ethnic group. the current study reviewed the root canal configuration of root canals in mandibular first and second premolars among iranian population based on independent epidemiological ...

background: mdm2 (murine double minute2) is an oncoprotein that inhibits the p53 activity. overexpression of mdm2 gene has been reported in several human tumors. in the present study, we aimed to evaluate the impact of 40-bp insertion/deletion (ins/del) polymorphism on the promoter of mdm2 and susceptibility to breast cancer in a sample of iranian population. methods: this case-control study wa...

background: proper rotation of components in total knee arthroplasty (tka) will largely affect the postoperative outcome. ethnical variation may affect rotational profile. we aimed to evaluate distal femur rotation in iranian population using transepicondylar axes.   methods : from a total of 450 knee ct scans and via consecutive sampling, 150 qualified subjects with normal lower extremities al...

BACKGROUND Assessing growth is a useful tool for defining health and nutritional status of children. The objective of this study was to construct growth reference curves of Iranian infants and children (0-6 years old) and compare them with previous and international references. METHODS Weight, height or length of 2107 Iranian infants and children aged 0-6 years old were measured using a cross...

BACKGROUND Cytochrome P450 2C19 (CYP2C19) is important in metabolism of wide range of drugs. CYP2C19*17 is a novel variant allele which increases gene transcription and therefore results in ultra-rapid metabolizer phenotype (URM). Distribution of this variant allele has not been well studied worldwide. The aim of present study was to investigate allele and genotype frequencies of CYP2C19*17 in ...

The Gilaki and Mazandarani occupy the South Caspian region of Iran and speak languages belonging to the North-Western branch of Iranian languages . It has been suggested that their ancestors came from the Caucasus region, perhaps displacing an earlier group in the South Caspian . Linguistic evidence supports this scenario, in that the Gilaki and Mazandarani languages (but not other Iranian lang...

Raana Zakeri, Shirin Nosratnejad. MSc of Health Services Management, School of Management and Medical Informatics, Iranian Center for Evidence-Based Medicine, Iranian Center of Excellence for Health Management, Tabriz University of Medical Sciences, Tabriz, Iran; PHD in Health Economic, Iranian Center of Excellence in Health Services Management, Department of Health Services Management, School ...

Mitra Torabi, Farnaz Naeemzadeh, Vida Ebrahimi, Negar Taleschian-Tabrizi, Fariba Pashazadeh, Hossein Nazemie. Students’ Research Committee, Iranian Evidence-Based Medicine Center of Excellence, School of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran; Students’ Research Committee, Iranian Evidence-Based Medicine Center of Excellence, School of Medicine, Tabriz University of Medic...

AIM To validate the association of variants in PNPLA3 (rs2281135) and TM6SF2 (rs58542926) genes with ultrasound detected non-alcoholic fatty liver disease (NAFLD). METHODS A total of 503 individuals with and without fatty infiltration were recruited. Fatty infiltration was confirmed based on ultrasound findings. Anthropometric data and blood samples were collected from the study group. DNA wa...