Aim In the present study, we investigated the prevalence of E. coli pathotypes and Shigella sero-groups and their antimicrobial profiles among diarrheic children in Nairobi city, Kenya. Background Although diarrheagenic E. coli pathotypes and Shigella sero-groups are leading causes of diarrhea in children under five years in developing countries, their distribution and antimicrobial resistanc...

Exposure to early life trauma (ELT) is known to have a profound impact on mental development, leading to a higher risk for depression and anxiety. Our aim was to use multiple structural imaging methods to systematically investigate how traumatic stressors early in life impact the emotional brain circuits, typically found impaired with clinical diagnosis of depression and anxiety, across the lif...

Postembryonic development in Caenorhabditis elegans is a powerful model for the study of the temporal regulation of development and for the roles of microRNAs in controlling gene expression. Stable switch-like changes in gene expression occur during development as stage-specific microRNAs are expressed and subsequently down-regulate other stage-specific factors, driving developmental progressio...

This paper reviews current critiques of Kolb’s experiential learning theory. Critiques converge on the belief that the theory places undo emphasis on the role of individual experience at the expense of social, political, and cultural elements of learning. This paper suggests that such critiques are based on a limited, selective, or simplistic reading of the initial theory. The theoretical relat...

We would like to thank Serge Mordon and his group for their stimulus to an important discussion, which was one of the aims of our paper to initiate. Our first series of experiments indicate that ELT leads to a wide variation in the effects on tissue within a certain treatment protocol. This may be due to a very complex mechanism of endovenous laser-induced thermal alteration. In ELT, energy lev...

Cells in a developing animal embryo become specified by the activation of cell-type-specific gene regulatory networks. The network that specifies gut nematode Caenorhabditis elegans has been subject study for more than two decades. In this network, maternal factors SKN-1/Nrf and POP-1/TCF activate zygotic GATA factor cascade consisting regulators MED-1,2 → END-1,3 ELT-2,7, leading to specificat...

Ground-conjugate wide eld AO is presented and preliminary performance results are given, which show that signi cant seeing improvement can be achieved over 10-20 arcmin eld of view. A proposal for an ELT AO system is sketched.

Comparative analysis between Caenorhabditis elegans and other nematode species offers a powerful approach to study gene function. C. elegans also has great potential as a surrogate expression system to study the function of genes from parasitic nematode species where transgenic methodologies are unavailable. However there is little information on the extent to which the biology of C. elegans is...

English as a lingua franca (ELF) research highlights the complexity and fluidity of culture in intercultural communication through English. ELF users draw on, construct, and move between global, national, and local orientations towards cultural characterisations. Thus, the relationship between language and culture is best approached as situated and emergent. However, this has chal­ lenged previ...

The importance of digital literacy has grown significantly, making its integration into English language teaching (ELT) crucial. This study investigated the role ELT in promoting among students at Muhammadiyah University Mataram and identified their needs. Using a mixed-methods research design, data were collected from students’ need through questionnaires interviews, which assessed skills, tec...