No way to treat a tumor O n page 93, Yuneva et al. provide bittersweet news for efforts to turn cancer cells’ big appetite against them. Contrary to previous work, the study shows that a sugar shortage snuffs out normal cells as well as cancer cells. But the results bolster another nutritional target: the amino acid glutamine. The idea that cancer cells hunger for glucose is more than 50 years ...

BACKGROUND The present study aimed to demonstrate the seasonal activities of Ixodes ricinus at the pasture level and on the host. METHODS A vast pasture in Amol countryside (Mazandaran Province, Iran) which had the potential for a considerable number of cattle and sheep to graze was chosen. Tick sampling from the skin of 130 cattle and 130 sheep were collected every month interval. Simultaneo...

involved, not least the leading player himself, Sir Henry Wellcome. So full praise to John Symons for having laid a firm path through this mixed vegetation and erected plain signposts to mark each succeeding stage on the way, as well as for the limpid prose ornamented by irony and understated wit with which he achieves this, to say nothing of his delightful footnotes. The section which speaks m...

“Nothing in biology makes sense except in the light of evolution” declared biologist Theodosius Dobzhansky in his seminal 1973 essay.1 This sentiment extends to aptamers, the topic highlighted in our special issue of Molecular Therapy—Nucleic Acids. Aptamers are short single-stranded oligonucleotides that can bind with high affinity and specificity to target molecules, and which are derived thr...