Background: Biopharmaceutical medicines represent a growing share of the global pharmaceutical market, and with many of these biopharmaceutical products facing loss of exclusivity rights, also biosimilars may now enter the biopharmaceutical market. Objectives: This study aims to identify and document which investment and development strategies are adopted by industrial players in the global bio...

Under the limitation of investment budget, a utility company is required to maximize the utilization of their existing assets during their life cycle satisfying both engineering and financial requirements. However, utility does not have knowledge about the status of each asset in the portfolio neither in terms of technical nor financial values. This paper presents a knowledge based model for th...

This paper seeks to analyze the way investors consider growth option values when pricing equity. To achieve this objective we study the effect on stock prices of a comparative case of direct foreign investment involving acquisition of two different growth options, whose valuation has already been well-documented in prior literature. The case consists of the two sequential investment stages carr...

NVESTORS, world over, are currently demanding more shareholder value than just high returns. Maximising shareholders value has always been the ultimate aim of every company. Investors are very keen in assessing the corporate financial performance that correlate with shareholders wealth particularly the market price of a share. Traditional performance measures like return on investment, earnings...

AbsIractThis paper applies Bayesian network tecbnique to model and inference tbe uncertain relationsbips among cost factors and benefit factors in E-services. A cost-benefit factor-relation modelproposed inour previous study isconsidered as domain knowledgeand tbe data collectedtbrougb a survey is as evidence to conduct inference. Tbrough calculating conditional probability distribution among f...

As the companies are more and more in media’s focus, there is a notable influence of media news on investment decisions. Our analysis relates the volume of positive or negative news in key newspapers with the evolution of the share prices of four main companies listed in the Bucharest Stock Exchange. A series of regression models helps us distinguish between the company-related variables which ...

The research at University College London School of Medicine (UCLSM) is supported by the Wellcome Trust, Action Research, the Special Trustees of University College Hospital, and the Muscular Dystrophy Group of Great Britain. The studies have been carried out with the assistance of Dr. P. S. Tofts, Mr. D. Delpy and Mr. A. Chu of the Department of Medical Physics (UCLSM), and Mr. N.Taylor of Kin...

System-initiated digressive proposals may be used to introduce new and unexpected information into automated telephone services. These digressions may be viewed as particularly pronounced forms of unsolicited interruptions as they contain information not directly related to the caller’s intended activity. In human–human conversation, interruptions are considered to be speech acts which intrinsi...