Background 99mTechnetium labelled 3,3-diphosphono-1,2-propanodicarboxylic acid (99mTc-DPD) scintigraphy has been repurposed in recent years as a sensitive non-invasive method for imaging transthyretin (ATTR) cardiac amyloid. We have routinely performed DPD scans since June 2010 at the National Amyloidosis Centre in London, and review here our findings in a large cohort of mostly British patients.

background: the aim of this study was to investigate the correlation between the cardiac and hepatic iron-overload as assessed by magnetic resonance imaging t2 star (mrit 2 -star) technique and serum ferritin level in patients with thalassemia major. methods: in this cross-sectional study we evaluated 170 patients in sayed shohada hospital in isfahan in the year of 2009, cardiac and hepatic iro...

UNLABELLED Myocardial fibrosis is always present in end-stage heart failure and is a major independent predictor of adverse cardiac outcome. Cardiac magnetic resonance (CMR) is an imaging method that permits a non-invasive assessment of the heart and has been established as the "gold standard" for the evaluation of cardiac anatomy and function, as well as for quantifying focal myocardial fibros...

BACKGROUND The aim of this study was to propose a method to estimate the maximum pressure in the left ventricle (MPLV) for a healthy subject, based on cardiac outputs measured by echo-Doppler (non-invasive) and catheterization (invasive) techniques at rest and during exercise. METHODS Blood flow through aortic valve was measured by Doppler flow echocardiography. Aortic valve geometry was calc...

The differential diagnosis of cardiac mass is important in determining the therapeutic plan and avoiding unnecessary surgical intervention. Non-invasive imaging methods would be useful in the diagnosis of suspected cardiac mass, because they may provide earlier diagnosis and more accurate assessment of cardiac mass. Native aortic valve thrombosis is a rare disorder and difficult to differentiat...

139 Interv. Cardiol. (2014) 6(2), 139–144 ISSN 1755-5302 Can you tell us a little bit about your background & what first drew you to the field of cardiovascular imaging & vascular interventional radiology? I graduated from Edinburgh Medical School (University of Edinburgh, Edinburgh, UK) in 1982 and went on to train in medicine and cardiology. I then become a research fellow at the Non-Invasive...

We report a case of sarcoidosis with an unusual presentation, initially manifesting as bilateral pulmonary embolism and then as a cardiac form of the disease with an ominous clinical event consisting of sustained ventricular tachycardia. The diagnosis was established by clinical and magnetic resonance criteria despite normal conventional echocardiographic study. Detailed functional assessment p...

Recent technological innovations in CT and MR imaging of the heart have vastly expanded the clinical utility of these modalities allowing them to complement and in some ways surpass the capabilities of more traditional methods. Cardiac MR (CMR) has an unrivaled ability to assess contractile function, characterize tissue, and detect minute areas of scar. In turn, CMR can reliably risk stratify i...