objective guillain-barre syndrome (gbs) is the most common cause of acute neuromuscular paralysis in children, its pathogenesis most probably involving an autoimmune response to schwann cell or peripheral nerve myelin antigens. steroid regimes improve demyelinating diseases such as chronic gbs. we assessed the benefit of high dose methylprednisolone (mp) combined with intravenous immunoglobulin...

x-linked agammaglobulinemia (xla) is a hereditary immunodeficiency, characterized by an early onset of recurrent bacterial infections, hypogammaglobulinemia and markedly reduced b lymphocytes number. in order to determine the association of neutropenia among iranian patients with xla, hospital records of 30 patients with confirmed xla in children medical center hospital, were reviewed. eight ou...

conclusions kd should be kept in mind as one of the causes of childhood acalculous cholestasis, abdominal discomfort and prolonged fever. case presentation we report a four-year-old boy with fever, abdominal pain, vomiting, jaundice and mild liver enlargement who gradually developed other signs of kd. he was treated by aspirin, intravenous immunoglobulin and finally methylprednisolone pulse the...

OBJECTIVES We conducted a case-control study to ascertain the clinical presentations, risk factors, and clinical outcomes of children who had Kawasaki disease and were admitted to the ICU of our children's hospital. METHODS We reviewed charts of all children who had a discharge diagnosis of Kawasaki disease and were admitted to the ICU from 1995 through 2007. For each patient, we identified 3...

OBJECTIVE Pain is a common symptom that affects quality of life in patients with post-polio syndrome. An increase in cytokine in the cerebrospinal fluid suggests that inflammation is pathophysiologically important in post-polio syndrome. Intravenous immunoglobulin might therefore be a therapeutic option. The aim of this study was to analyse the effect of intravenous immunoglobulin treatment on ...

Pediatric inflammatory multisystem syndrome temporally associated with COVID-19 is a potentially severe and rare condition that still needs better understanding to guide its management. Reports worldwide, especially in Latin America, are scarce. This report presents ten cases of pediatric children between 2 12 years old treated Peruvian hospital, diagnosed using the Centers for Disease Control ...

BACKGROUND Intravenous immunoglobulin rapidly decreases serum levels of intercellular antibodies in patients with pemphigus vulgaris. However, little is known about the effects of this therapy on antibodies directed specifically against desmoglein 1 and desmoglein 3 and on the IgG subclasses of these antibodies. This study was conducted to study the effect of intravenous immunoglobulin therapy ...