1 Russi E. Opiatinissbrauch. Medizinische Komplikationen. Stutt gart, Germany: G. Fischer, 1986; 1-10 2 Arnett EN, Battle WE, Russo J\@Roberts WC. Intravenous injection of talc-containing drugs intended for oral use. Am J Med 1976; 60:711-18 3 Tomashefski JE, Hirsch CS. The pulmonary vascular lesions of intravenous drug abuse. Hum Pathol 1980; 11:133-45 4 Kringsholm B, Christoffersen P Lung and...

Tianeptine is a selective serotonin reuptake enhancer, possessing strong antidepressant and anxiolytic properties. Its relative lack of sedative, anticholinergic and cardiovascular side effects makes it a highly tolerable substance of abuse. However, physical dependence quickly develops and withdrawal symptoms are common. Abusers in Georgia and Armenia use tianeptine by intravenous injection. D...

Intravenous injection of powdered tablets intended to oral use is a common practice among drug abusers, given the greater effectiveness attributed to accelerate delivery of the drug through this route compared to oral intake. This can result in both acute and chronic changes in the pulmonary vessels and parenchyma. Various terms have been used to describe this entity and include self-induced pu...

low molecular weight heparin-modified isoliquiritigenin-loaded solid lipid nanoparticle (lmwh-isl-sln) was developed for injective application. the morphological observation, particle diameter and zeta potential of lmwh-isl-sln were characterized using transmission electron microscopy (tem) and a malvern zetasizer. its entrapment efficiency (ee) and drug loading (dl) were determined by ultracen...

Low molecular weight heparin-modified isoliquiritigenin-loaded solid lipid nanoparticle (LMWH-ISL-SLN) was developed for injective application. The morphological observation, particle diameter and zeta potential of LMWH-ISL-SLN were characterized using transmission electron microscopy (TEM) and a Malvern Zetasizer. Its entrapment efficiency (EE) and drug loading (DL) were determined by ultracen...

Intravenous drug use has been a serious problem for Dublin's deprived inner city areas since the late 1970's. In 1985, a cohort of all known intravenous drug users (IVDUs) was identified in one inner city electoral cohort and has been followed since then. The cohort was identified before the introduction of HIV testing. The prevalence of HIV infection and its consequences have continued to rise...

Intravenous injection of powdered tablets intended to oral use is a common practice among drug abusers, given the greater effectiveness attributed to accelerate delivery of the drug through this route compared to oral intake. This can result in both acute and chronic changes in the pulmonary vessels and parenchyma. Various terms have been used to describe this entity and include self-induced pu...

The clinical effects of intravenous streptokinase in patients with acute myocardial infarction were compared with those of intracoronary streptokinase in a randomized, prospective study. Comparisons were also made with a historical control group. Fifty patients were entered into the study at 2.4 + 1.2 hr after onset of pain, and 27 were assigned to intravenous and 23 to intracoronary therapy. T...

infective endocarditis is a serious complication of intravenous (iv) drug abuse, with a reported mortality of 5 to 10%. a 21-year-old man, who was an intravenous drug abuser, presented with fever and dyspnea. transthoracic echocardiography showed a highly mobile, large vegetation on the anterior leaflet of the tricuspid valve. despite antibiotic therapy for ten days, the patient remained febril...