BACKGROUND/AIM The most important ethiology factor of chronic liver disease that progresses into terminal insufficiency is hepatitis C virus (HCV) infection. Intravenous (iv) drug abuse is the main cause for spreading HCV. Thus the therapy for such patients is of extreme importance in reducing the incidence of the disease. The aim of the study was to establish efficacy of a combined therapy wit...

conclusions combination therapy with surgical excision has a synergistic effect and appears to be the best treatment for extended lesions. however, new potent antibacterial drugs may help to improve the management of such infections when there are sufficient data on their in vitro activity. introduction nocardia species are described as opportunistic pathogens that mainly cause pulmonary nocard...

It has been estimated that there are now 800,000 active drug injecters living in the European Union. Drug injecting, which causes AIDS, is commonly practised among the drug abusers in this part of the world, where it quickly triggered a full-scale endemic of AIDS, HBV and HCV The various member-countries have responded in different ways. But the rates of infection are still alarmingly high ever...

Since the delta agent was first identified by Rizzetto and his colleagues in 1977 there has been much speculation regarding its nature and significance. The delta agent appears to be an RNA virus which is dependent on hepatitis B surface antigen (HBsAg) for its replication (Rizzetto et al, 1980). Chronic HBsAg carriers appear to be most at risk of developing delta infection (Smedile et al, 1981...

Patients with HIV-1 immune-related thrombocytopenia (HIV-1-ITP) have a unique Ab against platelet GPIIIa49-66 capable of inducing oxidative platelet fragmentation in the absence of complement. HIV-1-seropositive drug abusers are more prone to develop immune thrombocytopenia than non-drug abusers and have a higher coinfection with hepatitis C virus (HCV) than non-drug abusers (90% vs 30%). Molec...

A relationship between parental substance abuse and subsequent alcohol problems in their children has been documented extensively. Children of alcoholics (COAs) are considered to be at high risk because there is a greater likelihood that they will develop alcoholism compared with a randomly selected child from the same community. COAs and children of other drug-abusing parents are especially vu...

Objectives: To study the prevalence and psychosocial correlates of drug abuse among young adults aged 16-21 from upper socio-economic strata. The survey was conducted to identify certain psychosocial risk factors such as coping skills, independence/self-confidence, family communication, peer relationships and motivational factors for drug abuse among adolescents. Method: A cross-sectional surve...

Introduction Various treatment methods for drug abusers will result in different success rates. This is partly due to different neural assumptions and partly due to various rate of relapse in abusers because of different circumstances. Investigating the brain activation networks of treated subjects can reveal the hidden mechanisms of the therapeutic methods. Methods We studied three groups of...