AIM The aim of this article is to evaluate the rate of patients developing sustained elevated intraocular pressure (IOP) after ranibizumab (Lucentis) intravitreal (IVT) injections. DESIGN This is a retrospective study. PARTICIPANTS Charts of 192 consecutive patients receiving Lucentis for age-related macular degeneration (AMD) were retrospectively reviewed. MATERIALS AND METHODS We enroll...

Will Goldmann applanation tonometry, the age old “gold standard” of intraocular pressure (IOP) measurement, be replaced with newer methods? One of the newer methods of IOP measurement is PASCAL dynamic contour tonometry (DCT). A review of the history, scientific principles, clinical validation and clinical utility of DCT is presented.

The eyeball proptoses about 0.5 mM and increases in intraocular pressure (IOP) about 2 mmHg with voluntary widening of the lid fissure. The findings probably result from the retraction of the upper lid into the orbit, thus increasing the volume of orbit contents and forcing the eyeball forward. Decrease in IOP with repeated tonometry may result, in part, from decay of the increased pressure ind...

Methods: Ten eyes of 10 patients aged 26.5 6 5.7 (mean 6 SD) years with progressive keratoconus were treated with UV-A– riboflavin CXL and assessed with the Ocular Response Analyzer (ORA) that measured corneal hysteresis (CH), corneal resistance factor (CRF), Goldmann-correlated intraocular pressure (IOPg), and corneal compensated intraocular pressure (IOPcc). Intraocular pressure was also meas...

Four masked examiners studied the usefulness of the glass-rod for estimating intraocular pressure (IOP) in a living, anesthetized rabbit eye manometrically set to 135 different random values. With training, the average error in IOP estimation improved from 7.42 +/- 5.56 mmHg to 5.13 +/- 4.48 mmHg. Gentle palpation of the corneal apex with a glass-rod provides tactile and visual clues that may a...

Nitric oxide (NO) is able to lower intraocular pressure (IOP); however, its therapeutic effects on outflow physiology are location- and dose-dependent. A NO delivery platform that directly targets the resistance-generating region of the conventional outflow pathway and locally liberates a controlled dose of NO is reported. An increase in outflow facility (decrease in IOP) is demonstrated in a m...

A theoretical model demonstrates the influence of the globe's size on the effects of its intraocular pressure (IOP) and on its motility. Large globes seem more susceptible to the damaging consequences of elevated IOP, and move with greater difficulty than small ones. Routine measurement of axial length (AxL) may accordingly enhance precision in the diagnosis and management of glaucoma and strab...

METHODS: Consecutive patients with medically controlled OAG and visually significant cataracts were treated with ECP and cataract extraction (study group) or cataract extraction alone (control group). The groups were matched in age and baseline intraocular pressure (IOP). The main outcome measures were the change in IOP and number of glaucoma medications. Secondary measures included visual acui...

PURPOSE Intraocular pressure (IOP) spikes that occur during cyclocryotherapy for advanced glaucoma may further injure the already damaged glaucomatous optic nerve and be responsible for visual impairment that may occur after this treatment. The authors investigated the mechanism of pressure rise to see whether it can be avoided and thus prevent further optic nerve injury. The authors postulated...