BACKGROUND Catsper proteins are responsible for entering Ca(2+) to the cell and play an important role in sperm motility and male fertility. Antioxidants are vital for sperm motility too. Escanbil (Calligonum) extract possess some of the important antioxidant like Catechin and Quercetin. OBJECTIVE Here we investigated the effects of Escanbil (Calligonum) extract on the sperm parameters and th...

Objective(s): Phospholipase C ζ (PLCζ) is considered as a nominee for sperm associated oocyte activating factors and is located back-to-back with CAPZA3, an actin-capping protein controlling actin polymerization during spermiogenesis. They contain a common bidirectional promoter. The objective of this study was to identify individuals with parallel low expression of PLCζ and CAPZA3 mRNA, in hop...

background: in vitro fertilization (ivf) and intra cytoplasmic sperm injection (icsi) are recognized as established and increasingly successful forms of treatment for infertility, yet significant numbers of couples discontinue treatment without achieving a live birth. this study aims to identify major factors that influence the decision to discontinue ivf/icsi treatments. materials and methods:...

Fusion of sperm and egg plasma membranes is an early and essential event at fertilization but it is not known if it plays a part in the signal transduction mechanism that leads to the oscillations in the cytoplasmic free Ca2+ concentration ([Ca2+]i) that accompany mammalian egg activation. We have used two independent fluorescence methods and confocal microscopy to show that cytoplasmic continu...

The freezing and storage of the sperm are used cryopreservation germplasm in livestock breeding, genetic improvement indigenous species, preservation rare races, successful tolerance to environmental changes international exchanges. Both thawing process causes large volume cell fluid. Spermatozoon removes most its cytoplasm at differentiation stages lacks cytoplasmic component that contains ant...

Objective Infertility has an adverse effect on Quality of Life (QoL). The present study aimed to evaluate QoL and its effective factors in infertile couples. MaterialsAndMethods Fertility Quality of Life (FertiQoL) Instrument was used to measure QoL among 500 volunteer couplesattending the infertility clinic of Mother and Child Hospital in Shiraz, Iran. The participants’ demographic and clinica...

A study was made of the electrical and morphological changes in the sea-urchin oocyte during interaction with spermatozoa. The first event, a small step depolarization accompanied by a 20-40% decay in input resistance occurs within seconds of attachment. The evidence suggests that this electrical event is the result of sperm-oocyte fusion, and that the ion channels that lower the resistance acr...

BACKGROUND The integrity of DNA in spermatozoa is considered an additional parameter of semen quality and a potential fertility predictor. Significant progress has been made in recent years towards the development of reliable tests for sperm chromatin integrity and DNA damage assessment. However, most of the techniques available are labor intensive, require expensive instrumentation or utilize ...