background: today the use of natural substances plays a major role in improving the growth and immunity of aquatic organisms. objectives: the purpose of the present study was to evaluate the effects of iron nanoparticles with lactobacillus casei as a probiotic on growth parameters and probiotic counts in rainbow trout intestine. methods: seven hundred and twenty fish with 12±0.49 g initial weig...

It is difficult to model in vitro the intestine when seeking include crosstalk with gut microbiota, immune and neuroendocrine systems. Here we present a roadmap of current models facilitate choice in preclinical translational research focus on gut-on-chip. These micro physiological systems (MPS) are microfluidic devices that recapitulate physiology intestine. We ...

BACKGROUND: Diseases of the gastrointestinal tract are often accompanied by changes in oral cavity. This is largely due to morphological and functional unity mucosa entire digestive tract. Therefore, role a dentist important early oncological alertness for detecting malignant neoplasms at an stage their development.
 AIM: Present results study mucous membrane mouth animal during experiment...

Abstract Objective: Inflammatory bowel disease (IBD) is a complex inflammatory disease, for which few effective therapies exist. The goal of our current work was to show: i) that such complex, immune cell-driven pathogenesis could be captured on Emulate’s human Colon Intestine-Chips; and ii) this used as novel human-centric system support IBD drug development including anti-TNF-α antibodies. Me...