BACKGROUND The aim of our study is to investigate the immunohistochemical expression of E-cadherin in gastric carcinomas and in surrounding mucosa (normal or with lesions of chronic atrophic gastritis, intestinal metaplasia or dysplasia). MATERIAL AND METHODS We included 61 patients with gastric cancers operated in Emergency County Hospital Timisoara. We analyzed the E-cadherin immunohistoche...

A 37-year-old woman presented to the Internal Medicine Clinic with complaints of abdominal pain and constipation which had begun 3 months earlier. A colonoscopy was performed, and wall thickening of the sigmoid colon was detected. A biopsy of the sigmoid colon revealed a poorly differentiated, mucin-producing adenocarcinoma with a signet-ring pattern. No distant metastasis was detected. The pat...

CASE REPORT The case of a breast cancer patient with a progressive increase of CA 19.9 that indicated gastrointestinal metastasis is reported. After the observation of an increased CA 19.9 serum value (104.00; n.v. 0.0-37.00) a colonoscopy was performed. This examination showed the presence of an erythematous and granular zone near the ileocecal valve. Histological examination of biopsies taken...

Colorectal carcinomas are rare disease in the pediatric population, especially without known risk factors. The present article reports the case of a 15 year old boy with sporadic colon carcinoma who presented with acute intestinal obstruction symptoms during a soccer match. An annular colonic mass proximal to the hepatic flexure causing mechanical obstruction was observed on abdominal enhanced ...

Vasoactive intestinal peptide tumours (VIPomas) are rare pancreatic neuroendocrine tumours with an estimated incidence of between 0.2 to 0.5 per million per year that usually present with a conglomerate of findings related to the excessive secretion of vasoactive intestinal peptide (VIP) including profuse watery diarrhoea, dehydration, hypokalemia and hypoclorhydria occasionally referred to as ...

Angiosarcoma is a rare disease with a poor prognosis; significantly, patients with intestinal angiosarcomas who survive over 1 year after diagnosis are extraordinarily rare. This article describes the case of a 33-year-old gentleman who presented with abdominal pain of 4 months duration, which had increased in severity 2 weeks prior to presentation. After a complicated diagnostic and therapeuti...

Metastatic tumors involve the oral cavity, and the most common primary sites are the breast and lung. Most cases affect the mandible and maxilla in that order, although some of them can be located in the soft perioral tissues. We report the case of a 62-year-old male who had been diagnosed with sigmoid adenocarcinoma with nodal and liver metastasis, who presented 6 months later with a gingival ...