In volumetric brain imaging analysis, volumes of brain structures are typically assumed to be proportional or linearly related to intracranial volume (ICV). However, evidence abounds that many brain structures have power law relationships with ICV. To take this relationship into account in volumetric imaging analysis, we propose a power law based method-the power-proportion method-for ICV corre...

BACKGROUND Silver coating of the sewing ring (Silzone) was introduced as a modification of the St Jude Medical standard valve to provide antibacterial protection, but the valve has recently been withdrawn. OBJECTIVE To study patients with these prostheses to assess possible adverse effects, and to guide their follow up. DESIGN Prospective observational study of risk factors for stroke after...

Background: Silver coating of the sewing ring (Silzone) was introduced as a modification of the St Jude Medical standard valve to provide antibacterial protection, but the valve has recently been withdrawn. Objective: To study patients with these prostheses to assess possible adverse effects, and to guide their follow up. Design: Prospective observational study of risk factors for stroke after ...

BACKGROUND AND PURPOSE Brain size is commonly described in relation to ICV, whereby accurate assessment of this quantity is fundamental. Recently, an optimized MR sequence (QRAPMASTER) was developed for simultaneous quantification of T1, T2, and proton density. ICV can be measured automatically within minutes from QRAPMASTER outputs and a dedicated software, SyMRI. Automatic estimations of ICV ...

The autonomic nervous system (ANS) conveys neuronal input from the brain to the stomach. We investigated mechanisms through which urocortin 1 (UCN1) injected intracerebroventricularly (ICV, 300 pmol/rat) inhibits circulating ghrelin in rats. This was achieved by assessing (1) the induction of c-fos gene expression as a marker of neuronal activation in specific hypothalamic and caudal brainstem ...

Background: Calcitonin gene-related peptide (CGRP) and rat calcitonin (rCT) play critical roles in descending pain control systems. Objectives: The present research aimed to evaluate the effect of intracerebroventricular (ICV) administration CGRP rCT on mRNA expression peptides periaqueductal gray (PAG) healthy rats formalin test. Methods: A total 24 male Sprague Dawley were categorized into fo...

OBJECTIVE Pulmonary regurgitation may cause progressive right ventricular dilatation and dysfunction in adult patients previously repaired for right ventricular outflow tract obstruction (RVOTO), and who require subsequent valve implantation for relief of these symptoms. Right ventricular recovery after pulmonary valve implantation (PVI) may be closely linked to the functional importance of the...

BACKGROUND Patients who undergo tricuspid annuloplasty during left-side heart valve surgery have a poor postoperative clinical outcome. However, preoperative right ventricular (RV) echocardiography parameters that predict adverse events in these patients are poorly understood. METHODS AND RESULTS We studied 74 patients (age, 58±10 years; men, 27%) with significant tricuspid regurgitation who ...

introduction: ghrelin, increases food intake, decreases t3 and t4 concentrations and stimulates insulin release, while leptin reduces food intake and suppresses appetite. considering the importance of thyroid hormones, ghrelin and leptin in body metabolism, the purpose of this study was to investigate the effect of interactions between ghrelin and leptin (injected via icv route) and plasma t3 a...

Abstract To better understand the role of internal climate variability (ICV) in change impact studies, this study quantifies importance ICV [defined as intermember a single model initial-condition large ensemble (SMILE)] relation to anthropogenic (ACC; defined multimodel mean) global and regional using criterion time emergence (ToE). The uncertainty estimated ToE is specifically investigated by...