This study investigated the effectiveness of a new strategy, repeated radiofrequency (RF) ablation combined with ablated lesion elimination following transarterial chemoembolization (TACE)/transarterial embolization (TAE), for solitary huge hepatocellular carcinoma (SHHCC) 10 cm or larger. From July 2008 to October 2015, 39 consecutive patients with SHHCC were screened. Of these, 12 were treate...

In pixelated CdZnTe detectors, multiple interaction gamma-ray events are critical because they permit Compton imaging. However, in large-volume CdZnTe crystals, the depth of multiple interaction events is often poorly reconstructed due to significant nonuniformity of electron drift velocity while the depth of single interaction events can be accurately reconstructed using signal ratios. The non...

a total of 2519 blood samples were collected from five distinct populations of larestan, in fars province, in iran (lar, gerash, khour, latifi and berake) were examined for abo and rh blood groups. the gene frequencies obtained from these samples were compared with the hitherto reported corresponding data from other populations of fars province to determine the genetic structure of the larestan...

The aim of the present study was to elucidate the effectiveness of transcatheter arterial infusion chemotherapy (TAI) of the whole liver using an epirubicin-mitomycin-lipiodol emulsion, prior to radiofrequency thermal ablation (RFA), in preventing intrahepatic distant recurrence (IDR) from single hepatocellular carcinoma (HCC). Of the 269 consecutive patients who underwent RFA in our institute ...

Ecological drift causes species abundances to fluctuate randomly, lowering diversity within communities and increasing differences among otherwise equivalent communities. Despite broad interest in ecological drift, ecologists have little experimental evidence of its consequences in nature, where competitive forces modulate species abundances. We manipulated drift by imposing 40-fold variation i...

Nucleophosmin (NPM1/B23) is a nucleolar protein implicated in growth-associated functions, in which the RNA binding activity of B23 plays essential roles in ribosome biogenesis. The C-terminal globular domain (CTD) of B23 has been believed to be the RNA binding domain because the splicing variant B23.2 lacking the CTD binds considerably less efficiently to RNA. However, the recognition of targe...

Idiosyncratic drug reactions are a significant cause of morbidity and mortality for patients; they also markedly increase the uncertainty of drug development. The major targets are skin, liver, and bone marrow. Clinical characteristics suggest that IDRs are immune mediated, and there is substantive evidence that most, but not all, IDRs are caused by chemically reactive species. However, rigorou...

In this paper we present an efficient causal algorithm that can be used in multicast communication environments, in particular the overlapping multi-channel case, where a participant can belong and communicate through more than one multicast channel. The causal algorithm is built on the paradigm of group communication. The groups are established according to the participant channel subscription...

This paper presents the seismic performance of moment-resisting timber frame (MRTF). In Japanese urban areas, there are many small houses, and it is difficult to design a wooden building ensure both comfortable plan that effectively makes use constrained sites, also lacks flexibility in design. Therefore, expectations rising for high MRTF using residential members. this study, clarify dynamic b...

We investigated the efficacy of a novel microparticle (MP) based vaccine formulation consisting of pertussis toxoid (PTd), polyphosphazene (PCEP), CpG ODN 10101 and synthetic cationic innate defense regulator peptide 1002 (IDR) against Bordetella pertussis in mice. We studied whether encapsulation of these IDR-CpG ODN complexes into polyphosphazene-based microparticles further enhanced their im...