نتایج جستجو برای: interstitial cell tumor
تعداد نتایج: 1942181 فیلتر نتایج به سال:
background recent studies revealed that tumor-associated macrophages (tams) play a decisive role in the regulation of tumor progression by manipulating tumor oncogenesis, angiogenesis and immune functions within tumor microenvironments. signal transducer and activator of transcription 3 (stat3), which is a point of convergence for numerous oncogenic signalling pathways, is constitutively activa...
Due to progress in the research of glioma stem cells and the glioma niche, development of an animal model that facilitates the elucidation of the roles of the host tissue and cells is necessary. The aim of the present study was to develop a subcutaneous xenograft green fluorescent protein nude mouse model and use this model to analyze the roles of host cells in tumor necrosis repair. Tumors der...
objective: micrornas (mirnas) are a new class of non-coding rnas involved in regulating various biological processes including proliferation, differentiation, and apoptosis, among others. alterations in mirna expression are reported in several human cancers, which suggests their potential roles in tumor initiation and progression. members of the mir-302 cluster are highly expressed in embryonic...
Primary peritoneal clear cell carcinoma (PP-CCC), which is a rare tumor with poor prognosis, is typically managed with surgery and/or chemotherapy. We present a unique treatment approach for a patient with a pelvic PP-CCC, consisting of postchemotherapy intensity-modulated radiation therapy (IMRT) followed by interstitial high-dose-rate (HDR) brachytherapy. A 54-year-old female with an inoperab...
Fluid flow and chemokine gradients play a large part in not only regulating homeostatic processes the brain, but also pathologic conditions by directing cell migration. Tumor cells particular are superior at invading into brain resulting tumor recurrence. One mechanism that governs cellular invasion is autologous chemotaxis, whereby pericellular form due to interstitial fluid (IFF) leading migr...
The therapeutic efficacy of monoclonal antibodies (MAbs), bound to radionuclides, chemotherapeutic agents, toxins, growth factors, or effec tor antibodies, depends upon their ability to reach their target in vivo in adequate quantities. Despite the high vascular permeability and intersti tial transport coefficients in tumor tissue compared to several normal tissues, MAbs and their fragments do ...
Objective(s): The OCT4B1, as one of OCT4 variants, is expressed in cancer cell lines and tissues more than other variants and plays an important role in apoptosis and stress (heat shock protein) pathways. The present study was designed to determine the effects of OCT4B1 silencing on expressional profile of HSP40 gene family expression in three different human tumor cell lines. Materials and Met...
Germ cell tumors account for 2 to 3% of all cancers in children. These tumors appear in the testicles as painless masses. The primary treatment of these tumors is the removal of testicles and chemotherapy. Giant cell tumor of the tendon sheath (GCTTS) is slow-growing tumor and the primary treatment of this tumor is surgery and both surgery and radiotherapy in invasive type. This report presents...
Pneumoconioses are a group of non-neoplastic pulmonary disorders caused by inhaled inorganic particles. Welldescribed forms of pneumoconiosis include those from asbestos, silica, coal dust, beryllium, and hard metals. Giant-cell interstitial pneumonia is an uncommon pneumoconiosis, usually due to exposure to hard-metal compounds, primarily cobalt and tungsten carbide. The natural course of the ...
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