INTRODUCTION Anal fissure is an ischemic ulcer caused by combination of spasm of internal anal sphincter and poor blood supply to the posterior midline of anal canal. This study aimed to assess the efficacy of Glyceryl Trinitrate and Nifedipine in the treatment of chronic anal fissure. METHODS Ninety patients with symptomatic anal fissure in Kathmandu Medical College Teaching Hospital are all...

This study evaluates whether reflux function of the anal sphincter remains unchanged after restorative proctocolectomy, provided that the sphincter remaining is kept intact, without mucosal stripping or endo-anal anastomosis. Paired tests of anorectal function were performed before, and a median of 6 (range 2-12) months after restorative proctocolectomy with stapled, end to end pouch-anal anast...

2014 Anal fissure is a common painful anorectal condition which affects people of various age groups, and deteriorates their quality of life. Chronic anal fissure requires medical intervention either by pharmacotherapy or by surgery. Various pharmacological agents have been used in the treatment of chronic anal fissure with the aim of relaxation of internal anal-sphincter smooth muscle. Diltiaz...

AIM To compare surgical and chemical sphincterotomy for treatment of chronic anal fissure. METHODS The 160 patients studied were randomly divided into four equal groups, treated by lateral internal sphincterotomy (group S), local diltiazem ointment (group D), local glyceryl trinitrate ointment (group GTN), or injection of botulinum toxin into the internal anal sphincter (group BT). Anal manom...

1. Corby H, Donnelly VS, O’Herlihy C, O’Connell PR. Anal canal pressures are low in women with postpartum anal fissure. Br J Surg 1997;84:86-8. 2. Frudinger A, Halligan S, Bartram CI, Price AB, Kamm MA, Winter R. Female anal sphincter: age-related differences in asymptomatic volunteers with high-frequency endoanal US. Radiology 2002;224:417-23. 3. Farouk R. Sphincter-preserving therapy for trea...

The aim of the study was analysis of an anal sphincter function in patients before and after surgery for rectal prolapse. Material and methods. Between 1987 and 2005, 49 patients underwent operations for rectal prolapse. The anal sphincter function was analyzed in 17 of these patients. Abdominal approach surgery was performed in 13 patients; this involved rectopexy in 11 and sigmorectal resecti...