Salinity stress is one of the marked influencing factors on ecophysiology aquaculture and considered an important reason for retreat fish industry. The current study endeavor to elucidate molecular mechanisms that underlie response salinity in common carp. Fish (Average weight 5 ± 2 g) were randomly distributed into two groups; 1 st a control was exposed tap water (0.2 ppt salinity) nd treated ...

Blautia has attracted attention because of its potential efficacy in ameliorating host energy metabolism and inflammation. This study aims to investigate the influences producta D4 on colitis induced by dextran sulfate sodium (DSS) reveal underlying mechanisms. Results showed that B. producta intervention significantly relieved body weight loss, suppressed elevation pro-inf...

Atherosclerosis is characterized by localized lesions distributed in the arterial tree due to the shear stress produced by blood flow. Endothelial cells are directly affected by alterations in blood flow. Dysfunction and injury to endothelial cells has been hypothesized to initiate the pathological processes of atherosclerosis. The present study aimed to investigate the mechanism of shear stres...

Abstract Background Tramadol provokes oxidative stress that gives rise to apoptosis with alterations in the cellular structure and adversely influences male fertility. A specific inhibitor of nuclear factor kappa B (NF-κB), pyrrolidine dithiocarbamate (PDTC), has observable antioxidant anti-inflammatory characteristics enhances improvement organs damage caused by various agents. The impact PDTC...

Inflammation is closely related to the progression of cancer as well as tumorigenesis. Here, we investigated the effect of prostaglandin E(2) (PGE(2)) and interleukin-1β (IL-1β) on E-cadherin expression in SNU719 gastric cancer cells. E-cadherin expression decreased as the dose or exposure time of PGE(2) and IL-1β increased, whereas Snail expression increased with dose or time of PGE(2) and IL-...