BACKGROUND We investigated whether intensive glycemic control, combination therapy for dyslipidemia, and intensive blood-pressure control would limit the progression of diabetic retinopathy in persons with type 2 diabetes. Previous data suggest that these systemic factors may be important in the development and progression of diabetic retinopathy. METHODS In a randomized trial, we enrolled 10...

Intensive care unit-acquired weakness is a common complication of critical illness leading to severe functional impairment in many intensive care unit survivors. Critically ill patients who require mechanical ventilation are routinely immobilized for prolonged time periods. This immobilization is exacerbated by frequent administration of sedative agents. Recently, several investigators have des...

Acute renal failure requiring renal replacement therapy (RRT) is a frequent complication in critically ill patients with high morbidity and mortality. Early prediction of who is going to need RRT is clinically useful in the intensive care unit (ICU). Patients' with diuretic resistant pulmonary edema, hyperkalemia/metabolic acidosis refractory to medical therapy and uremic complications (pericar...

BackgroundMany studies reported that copper, zinc and magnesium play important roles in the pathogenesis and development of neonatal hyperbilirubinemia. Exchange transfusion and intensive phototherapy are known two modalities of therapy for severe neonatal hyper bilirubinemia, but the effect of them on those trace elements is unknown.Materials and MethodsCopper, Zinc and Magnesium serum levels ...

Acute myeloid leukemia (AML) is most common in the elderly, and most elderly are thought to be unfit for intensive treatment because of the risk of fatal toxicity. The Swedish Acute Leukemia Registry covers 98% of all patients with AML (nonacute promyelocytic leukemia) diagnosed in 1997 to 2005 (n = 2767), with a median follow-up of 5 years, and reports eligibility for intensive therapy, perfor...

BACKGROUND Intensive insulin therapy reduces morbidity and mortality in patients in surgical intensive care units (ICUs), but its role in patients in medical ICUs is unknown. METHODS In a prospective, randomized, controlled study of adult patients admitted to our medical ICU, we studied patients who were considered to need intensive care for at least three days. On admission, patients were ra...

BACKGROUND Hyperglycemia is common among patients admitted to intensive care units, and carries the risk for complications and prolonged ICU stay. With intensive insulin control of blood glucose, morbidity and mortality can be reduced. OBJECTIVES To determine whether intensive or conventional insulin control of blood glucose in hyperglycemic ICU patients correlated with the prognosis. METHO...

OBJECTIVE To review the most important aspects of the clinical presentation and treatment of children with cancer in intensive care units. SOURCE OF DATA Medline (1970 to 2003); search terms: children, cancer, oncology, intensive care, complications. General and pediatric oncology textbooks. SUMMARY OF THE FINDINGS Practically all organs may be affected by cancer or by its treatment. The ma...