The Guidelines Project, an initiative of the Brazilian Medical Association, aims to combine information from the medical field in order to standardize procedures to assist the reasoning and decision-making of doctors. The information provided through this project must be assessed and criticized by the physician responsible for the conduct that will be adopted, depending on the conditions and th...

The treatment of cancer of the anal canal has changed significantly over the past several decades. Although the abdominoperineal resection (APR) was the historical standard of care, a therapeutic paradigm shift occurred with the seminal work of Nigro, who reported that anal canal cancer could be treated with definitive chemoradiation, with APR reserved for salvage therapy only. This remains an ...

IMRT / 1 The American College of Radiology, with more than 30,000 members, is the principal organization of radiologists, radiation oncologists, and clinical medical physicists in the United States. The College is a nonprofit professional society whose primary purposes are to advance the science of radiology, improve radiologic services to the patient, study the socioeconomic aspects of the pra...

IMRT treatment planning via biological objectives gives rise to constrained nonlinear optimization problems. We consider formulations with nonlinear objectives based on the equivalent uniform dose (EUD), with bound constraints on the beamlet weights, and describe fast, flexible variants of the two-metric gradient-projection approach for solving them efficiently and in a mathematically sound man...

Radiation therapy has been one of the major treatment modalities for the prostate cancer over the past few decades. Treatment planning system (TPS) is an integral component in radiation therapy in order to ensure the accurate estimation of radiation dose to the tumor. However, due to the variability in optimization techniques and beam modeling among various TPS, the current literature on radiat...

Volumetric modulated arc therapy (VMAT) and intensity modulated radiation therapy (IMRT) are commonly used treatment techniques for cancer treatment, and both the VMAT and IMRT techniques use the photon beam (mega-voltage X-rays) to deliver radiation dose to the tumor. The capability of modulating radiation beam has increased the ability of delivering more conformal dose distributions to tumor ...

Introduction: Electronic portal imaging devices (EPIDs) are extensively used for dosimetric information of pre-treatment field verification and in-vivo dosimetry for Intensity Modulated Radiotherapy (IMRT). In the present work, we have implemented the newly developed portal dosimetry software using independent dose prediction algorithm EPIDose and evaluated this new tool for the pretreatment IM...

The Simultaneous Nadir Overpass (SNO) method developed at NOAA/NESDIS has been used for the intersatellite calibration in the last few years with excellent results. The objective of this project is to establish and apply an accurate intersatellite calibration procedure to develop inter-satellite calibration data sets and characterize inter-satellite calibration bias, which will be useful for da...

BACKGROUND Research regarding the decision to adopt and implement technological innovations in radiation oncology is lacking. This is particularly problematic since these technologies are often complex and rapidly evolving, requiring ongoing revisiting of decisions regarding which technologies are the most appropriate to support. Variations in adoption and implementation decisions for new radia...