While much work has been done in the design of biomaterials to control integrin-mediated adhesion, less emphasis put on functionalization materials with cadherin ligands. Yet, cell–cell contacts combination cell–matrix interactions are key driving embryonic development, collective cell migration, epithelial mesenchymal transition, and cancer metastatic processes, among others. This review focus...

BACKGROUND Impaired platelet function has been reported in acute myocardial infarction (AMI) and stroke. However, prospective data on the changes of platelet status in patients before the occurrence of hemorrhagic stroke after thrombolytic therapy are unavailable. CASE DESCRIPTION An 86-year-old male patient was among the 23 AMI patients enrolled in the platelet study for the GUSTO-III trial....

We previously reported peritoneal innate-like integrin α4 (CD49d)highCD4+ T cells that provided help for B-1a cells. Here we analyzed the expression of various integrin chains on the peritoneal and pleural integrin α4highCD4+ T cells and investigated the functional heterogeneity of the subpopulations based on the integrin expression. Pleural cavity contained a lower ratio of integrin α4highCD4+...

ENWEndNote BIBJabRef, Mendeley RISPapers, Reference Manager, RefWorks, Zotero AMA Biegańska EA, Rokicki K, Karolewska-Bochenek Łazowska-Przeorek I, Banasiuk M. Anti-integrin treatment as an effective alternative for a patient with ulcerative colitis. Pediatria Polska - Polish Journal of Paediatrics. 2022;97(4):347-350. doi:10.5114/polp.2022.123917. APA Biegańska, E. A., Rokicki, K., Karolewska-...

Abstract CD157 is an ectoenzyme that has both cyclic ADP-ribose hydrolase and ADP-ribosyl cyclase activities. In the human hematopoietic system, prevalently expressed by cells of myelomonocytic lineage, interacts with extracellular matrix components regulates leukocyte diapedesis via integrin-mediated signaling. implicated in pathophysiology several neurological disorders. Although it lacks a c...

Nascent adhesions (NAs) are a general precursor to the formation of focal (FAs) that provide fundamental mechanism for cell adhesion is, in turn, involved proliferation, migration, and mechanotransduction. form when cells come into contact with substrates at all rigidities generally involve clustering ligated integrins may recruit un-ligated integrins. tend take on characteristic sizes range O(...

the hallmarks of leukocyte adhesion deficiency (lad) are defects in the leukocyte adhesion process, marked leukocytosis and recurrent infections. these molecular and clinical manifestations result from an impaired step in the inflammatory process, namely, the emigration of leukocytes from the blood vessels to sites of infection, which requires adhesion of leukocytes to the endothelium. over las...

The Effect of Silybinin on the Expression Vascular Endothelial Growth Factor (VEGF) and Integrin-linked kinase (ILK) in Olfactory Ensheathing Cells under Normal High Glucose Conditions