Chromatin insulators are functionally conserved DNA-protein complexes situated throughout the genome that organize independent transcriptional domains. Previous work implicated RNA as an important cofactor in chromatin insulator activity, although the precise mechanisms are not yet understood. Here we identify the exosome, the highly conserved major cellular 3' to 5' RNA degradation machinery, ...

Photoinduced phase transitions in organic compounds with strong electron correlation ET [bis(ethylenedithio)-tetrathiafulvalene)-based salts α-(ET)2I3, θ-(ET)2RbZn(SCN)4, κ-(d-ET)2Cu[N(CN)2Br] were discussed based, on time resolved optical pump-probe spectroscopy using ~150 fs mid-infrared pulse, 12 fs near infrared pulse, and sub-picosecond terahertz pulse. (i) In charge-ordered insulators α-(...

Insulators are DNA sequences thought to be important for the establishment and maintenance of cell-type specific nuclear architecture. In Drosophila there are several classes of insulators that appear to have unique roles in gene expression. The mechanisms involved in determining and regulating the specific roles of these insulator classes are not understood. Here we report that DNA Topoisomera...

A new thermodynamic phase resulting from the competition between a commensurate potential and disorder in interacting fermionic or bosonic systems is predicted. It requires interactions of finite extent. This phase, intermediate between the Mott insulator and the Anderson insulator, is both incompressible and has no gap in the conductivity. The corresponding phase is also predicted for commensu...

"Load-locked dc high voltage GaAs photogun with an inverted-geometry ceramic insulator" (2010). A new dc high voltage spin-polarized photoelectron gun has been constructed that employs a compact inverted-geometry ceramic insulator. Photogun performance at 100 kV bias voltage is summarized.

DREF was first characterized for its role in the regulation of transcription of genes encoding proteins involved in DNA replication and found to interact with sequences similar to the DNA recognition motif of the BEAF-32 insulator protein. Insulators are DNA-protein complexes that mediate intra- and inter-chromosome interactions. Several DNA-binding insulator proteins have been described in Dro...

Insulators are cis-elements that control the direction of enhancer and silencer activities (enhancer-blocking) and protect genes from silencing by heterochromatinization (barrier activity). Understanding insulators is critical to elucidate gene regulatory mechanisms at chromosomal domain levels. Here, we focused on a genomic region upstream of the mouse Ccnb1ip1 (cyclin B1 interacting protein 1...

In order to avoid the impacts of outer factors on the ice-covered insulators recognition, such as weather, seasons, outside illumination changes, acquisition time, image background and image contrast, a general algorithm which can recognize and detect the ice-covered insulator accurately in a complex environment is put forward in this paper. With the video monitoring device, the image informati...

This paper reports on the selection of insulating material types in a developed atmosphericpressure non-thermal plasma jet (ANPJ-II) device which was operated previously in our laboratory based on the minimum erosion area of the insulator’s nozzle. Three identical insulator groups used in our experiment include; Teflon insulator material with different thicknesses of 1.5 mm and 2 mm respectivel...